摘要: |
心肌细胞电生理机制的阐明和细胞移植技术的迅速发展,为治疗各类心脏疾病开辟了新的思路。近年来,国外学者报道了多种细胞移植的方法,以探索细胞移植治疗各类缓慢型心律失常的可行性,如完全性心脏传导阻滞和病窦综合征等。目前已经取得了一定的研究成果。本文总结了现有方法各自存在的优势和不足,并对生物起搏器的发展前景做一展望。 |
关键词: 细胞移植 心律失常 心脏起搏器 生物 |
DOI:10.3724/SP.J.1008.2007.00001 |
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基金项目:国家自然科学基金(30672075). |
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Cell transplantation in treatment of bradyarrhythmias: an update |
XU Zhi-yun ,ZHANG Hao |
(Department of Cardiothoracic Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China) |
Abstract: |
The deepening of our understanding on the cardiac electrophysiology mechanism and the progress on cell transplantation technique have expanded our view in treating various kinds of cardiac diseases. Over the past few years literatures have reported many kinds of cell transplantation techniques for treating various types of bradyarrhythmias, such as complete heart block and sinoatrial node dysfunction, and impressive achievements have been made by far. This review discusses the advantages and flaws of the existing strategies and the future of biological pacemakers |
Key words: cell transplantation arrhythmia pacemakers, biological |