| 摘要: |
| 碱性成纤维细胞生长因子（basic fibroblast growth factor,bFGF）是体内重要的创伤愈合因子之一。骨折后bFGF通过调控骨组织中细胞增殖及分化、增加骨折局部骨密度及促进局部血管生成来加速骨折的愈合。此外,随着对bFGF研究的不断深入,其在骨组织工程所展现出的对骨修复的作用将越来越受到人们的重视。[ |
| 关键词: 成纤维细胞生长因子2 骨折愈合 信号传导 |
| DOI：10.3724/SP.J.1008.2007.00329 |
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| 基金项目: |
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| Role of basic fibroblast growth factor in promoting fracture healing and the related mechanism |
| YIN Hui-jun, SU Jia-can |
| (Department of Orthopedics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China) |
| Abstract: |
| Basic fibroblast growth factor（bFGF） is one of the most important factors for wounds healing. BFGF promotes healing of bone fracture by regulating cell proliferation and differentiation of bone tissues, increasing local bone density, and accelerating local angiogenesis. With the progression of bFGF research, more and more attention will be paid to bone repair function of bFGF in bone tissue engineering.[ |
| Key words: fibroblast growth factor 2 fracture healing signal transduction |
