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心理应激对认知功能的影响及有关神经机制研究进展
潘昱1,程祺2,严进3*
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(1.解放军总医院医学心理科,北京 100853*2.解放军第102医院精神科,常州 213001*3.第二军医大学心理学教研室,上海 200433)
摘要:
心理应激是机体通过认识、评价而察觉到应激原的威胁时引起的心理、生理机能改变的过程。由于心理应激几乎总是伴随情绪反应,以往对于心理应激对认知功能影响的研究多在一定情绪状态下进行。最近的研究表明应激所致糖皮质激素升高和应激引发情绪反应所致儿茶酚胺和糖皮质激素升高对认知功能有不同影响,本文对此作一综述。
关键词:  心理应激  认知  神经化学  糖皮质激素  儿茶酚胺
DOI:10.3724/SP.J.1008.2009.00084
投稿时间:2008-01-07修订日期:2008-11-24
基金项目:国家自然科学基金(30572080);军队医药卫生科研基金“十五规划”面上项目(04M021),军队医药卫生科研基金“十一五规划”专项研究项目(06Z043),军队医药卫生科研基金“十一五规划”科技攻关项目(06G036).
Effects of psychological stress on cognitive function and the related neurochemical mechanism:recent progress
PAN Yu1,CHENG Qi2,YAN Jin3*
(1.Department of Medical Psychology,General Hospital of PLA,Beijing 100853,China*2.Department of Psychiatry,No.102 Hospital of PLA,Changzhou 213001*3.Department of Psychology,Second Military Medical University,Shanghai 200433)
Abstract:
Psychological stress refers to the process of psychological,physiological function changes induced by perceived threat of the original stress through cognition and evaluation.Psychological stress is almost always accompanied by emotional reactions,so previous studies on influence of psychological stress on the cognitive function were carried out under certain emotional state.Recent studies have shown that stress-induced glucocorticoid increase and catecholamine and glucocorticoid increase caused by stress-induced emotional reactions have different effects on cognitive functions,which is reviewed in this article.
Key words:  psychological stress  cognition  neurochemical  glucocorticoid  catecholamine