【打印本页】 【下载PDF全文】 【HTML】 查看/发表评论下载PDF阅读器关闭

←前一篇|后一篇→

过刊浏览    高级检索

本文已被:浏览 3357次   下载 3487 本文二维码信息
码上扫一扫!
创伤后应激障碍脑结构影像学改变研究进展
王淑珍1*,傅建设2,王芳3
0
(1.西北大学公共管理学院应用心理学研究所,西安 710127; 2.西安交通大学第二附属医院影像中心,西安 710004;3.三原县人民医院B超室,咸阳 713800)
摘要:
通过综述创伤后应激障碍(PTSD)脑结构影像变化的相关研究及其最新进展,阐明了PTSD患者相关脑区体积、灰质、白质密度的减小,主要表现为海马、胼胝体与前扣带回等区域脑结构影像的变化,其中,PTSD患者胼胝体的变化具有特异性;指出了白质与灰质结构影像分析是目前该研究领域中前沿性和战略性的两个研究方向;同时提出了PTSD与脑结构影像变化的因果关系研究是今后该领域亟待研究解决的课题。
关键词:  创伤后应激障碍  脑结构影像  脑体积  脑灰质  脑白质
DOI:10.3724/SP.J.1008.2009.0305
投稿时间:2008-10-29修订日期:2009-02-10
基金项目:教育部重点课题(DBB010502).
Imaging changes of brain structure in post-traumatic stress disorders: recent progress
WANG Shu-zhen1*, FU Jian-she2, WANG Fang3
(1. Institute of Applied Psychology, School of Public Administration, Northwest University, Xi′an 710127,China;2. Center of Imaging, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004;3. Department of B-ultrasonic,The Peoples’ Hospital of Sanyuan County, Xianyang 713800)
Abstract:
The brain structural imaging changes in patients with post-traumatic stress disorders (PTSD) and the related research progress are reviewed. It is elucidated that the volume decrease and the density reductions of gray and white matters in PTSD patients are mainly manifested as the imaging changes of the hippocampus, callus, and anterior cingulate cortex (ACC). The imaging change of callus is characteristic in PTSD patients. The image structure analyses of the white matter and gray matter are the current frontiers and strategic trends of PTSD-related research. Meanwhile, it is pointed out that the relationship between PTSD and brain structure imaging is a problem needs to be urgently solved.
Key words:  post-traumatic stress disorders  brain structural imaging  brain volume  gray-matter  white-matter