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颈动脉彩色多普勒超声检测指标与经颅多普勒超声参数值间的相关性分析
康庆云,宋治*,黄献,郑文,贺国华
0
(中南大学湘雅三医院神经内科,长沙 410013)
摘要:
目的对颈动脉彩色多普勒超声(CDFI)各检测指标与经颅多普勒超声(TCD)各参数值进行相关性分析,探讨CDFI各检测指标与TCD各参数值间的相关性。方法选取2008年3月至2009年3月在我院神经内科住院的118例缺血性脑血管病患者作为研究对象,所有研究对象均同时完善了CDFI及TCD检查。首先将118例患者分为有、无斑块两组行成组t检验,探讨颈动脉粥样硬化斑块有无与TCD参数值间的相关性;另将研究对象分为无斑块组、单侧斑块组和双侧斑块组,对3组资料进行单因素方差分析及SNK-q检验,探讨斑块数量与TCD参数值间的相关性;并将斑块组分为硬斑组、软斑组和混合斑组3个亚组,亦对该3组资料进行单因素方差分析及SNK-q检验,探讨斑块性质与TCD参数值间的相关性;最后对左颈总动脉内中膜厚度(IMT)与TCD参数值进行直线相关分析,分析IMT与TCD参数值间的相关性。结果与无斑块组相比,斑块组的左侧大脑中动脉(LMCA)、右侧大脑中动脉(RMCA)及基底动脉(BA)的PI、RI、S/D值升高,差异有统计学意义(P<0.05),而Vp、Vd、Vm无统计学差异。斑块数量、斑块性质、IMT与TCD参数值无相关性。结论除有无颈动脉粥样硬化斑块外,其余各CDFI检测指标与TCD检测结果无相关性,联合应用CDFI、TCD能较全面地反映脑血管结构及血流动力学状况,为临床诊治疾病提供参考。
关键词:  脑缺血  颈动脉  彩色多普勒超声检查  经颅多普勒超声检查
DOI:10.3724/SP.J.1008.2010.0634
投稿时间:2009-11-04修订日期:2010-03-30
基金项目:
Correlation analysis of carotid artery color Doppler flow imaging indices and transcranial Doppler ultrasound indices
KANG Qing-yun, SONG Zhi*, HUANG Xian, ZHENG Wen, HE Guo-hua
(Department of Neurology, the Third Xiangya Hospital, Central South University, Changsha 410013, Hunan,China)
Abstract:
ObjectiveTo analyze the correlation of carotid artery color Doppler flow imaging (CDFI) indices and transcranial Doppler ultrasound (TCD) indices.MethodsThe clinical data of 118 hospitalized patients with ischemic cerebrovascular diseases were included in the present study and all of them received CDFI and TCD examination. The patients were divided into two groups according to presence of carotid plaque group; t-test was used to identify the correlation between the presence of carotid plaque and TCD indices. Meanwhile, the patients were also divided into three groups according to the quantity/distribution of plaque; one-way ANOVA(F-test) and student-Newman-Keuls were used to identify the correlation of the quantity/distribution of plaque with TCD indices. The patients with carotid plaque were divided into three groups according to the plaque texture; one-way ANOVA(F-test) and student-Newman-Keuls were used to identify the correlation of the quality of plaque with TCD indices. Meanwhile, linear correlation was used to identify the correlation of the common carotid intimal-medial thickness(CCA IMT) with TCD indices.ResultsThe resistance index (RI), pulsatile index (PI) and ratio of peak systolic to least diastolic flow velocity (S/D) of bilateral middle cerebral arteries and basal artery in patients with carotid plaque were significantly higher than those in patients without carotid plaque(P<0.05); other TCD indices including Vp, Vd, and Vm were not significantly different. The quantity/distribution of plaque, the quality of plaque and CCA IMT were not correlated with TCD indices. ConclusionNo CDFI indices, except for the presence of carotid plaque, are correlated with TCD indices. Combined application of CDFI and TCD indices can better reflect the structure and hemodynamic status of cerebral vessels.
Key words:  brain ischemia  carotid artery  color Doppler ultrasonography  transcranial Doppler ultrasonography