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良恶性腹水鉴别诊断的实验室检查指标
罗蕾蕾1,2,陈建2,邵建国2*
0
(1. 南京中医药大学第一临床医学院,南京 210046; 2. 南通市第三人民医院消化内科,南通 226006)
摘要:
良恶性腹水的鉴别诊断在临床上具有极其重要的意义,尤其是恶性腹水的早期诊断相对更困难。临床上常规应用细胞学检查寻找癌细胞而确诊,但漏诊率较高,且阴性结果并不能排除肿瘤可能。越来越多新的检查方法和指标在临床工作中得到应用,取得初步成效,为良恶性腹水的鉴别诊断提供了依据。本文就良恶性腹水鉴别诊断的实验室检查指标研究进展作一综述。
关键词:  腹水  鉴别诊断  端粒酶  DNA倍体分析
DOI:10.3724/SP.J.1008.2010.0674
投稿时间:2009-12-25修订日期:2010-05-28
基金项目:
Laboratory indicators for differential diagnosis of benign and malignant ascites
LUO Lei-lei1,2, CHEN Jian2, SHAO Jian-guo2*
(1. The First College of Clinical Medicine, Nanjing University of Tranditional Chinese Medicine, Nanjing 210046, Jiangsu, China; 2. Department of Gastroenterology, The Third People’s Hospital of Nantong, Nantong 226006, Jiangsu, China)
Abstract:
The differential diagnosis of benign and malignant ascites is of great significance in clinic; the early diagnosis of malignant ascites is especially difficult. Definite diagnosis is usually based on conventional cytology to find cancer cells in the ascites in clinic, but the rate of missed diagnosis is high, and the negative outcome cannot exclude the presence of tumors. Currently, many new laboratory methods and indicators have been used clinically and have demonstrated primary efficiency in providing evidences for differential diagnosis of benign and malignant ascites.This article reviews the progress in laboratory indicators for differential diagnosis of benign and malignant ascites.
Key words:  ascites  differential diagnosis  telomerase  DNA ploidy analysis