| 摘要: |
| 目的探讨老年2型糖尿病患者睡眠质量与轻度认知功能损害的关系。方法97例老年2型糖尿病患者分为轻度认知功能损害组(DM-MCI)与认知功能正常组(DM-NC)，均使用简易智能状态检查量表、蒙特利尔认知评估量表、焦虑自评量表、流调用抑郁自评量表、日常生活能力量表、全面衰退量表以及匹茨堡睡眠质量指数量表等进行测验，对测验结果进行两独立样本的t检验和Spearman等级相关分析。结果DM-MCI组催眠药使用情况明显增多(P=0.046)，与延迟回忆的负相关(r=-0.277)未达到统计学意义(P=0.062)；DM-MCI组匹茨堡睡眠质量指数量表总分与蒙特利尔认知评估量表总分(r=-0.362)、匹茨堡睡眠质量指数量表总分与注意(r=-0.319)、匹茨堡睡眠质量指数量表总分与延迟回忆(r=-0.409)、日间功能障碍与蒙特利尔认知评估量表总分(r=-0.393)、日间功能障碍与抽象(r=-0.337)、夜间睡眠障碍与语言(r=-0.439)、睡眠效率与延迟回忆(r=-0.325)、主观睡眠质量与延迟回忆(r=-0.336)均存在有统计学意义的负相关(P<0.05)。结论老年2型糖尿病患者睡眠质量与其轻度认知功能损害的部分表现间存在相关性。 |
| 关键词: 老年人 2型糖尿病 睡眠质量 认知障碍 |
| DOI：10.3724/SP.J.1008.2011.0404 |
| 投稿时间：2011-01-23修订日期：2011-03-30 |
| 基金项目: |
|
| Correlation analysis between sleep quality and mild cognitive impairment in elderly patients with type 2 diabetes mellitus |
| LUO Lan1 2,TUO Xi-ping1*,ZHANG Wen-jun1,BAI Jie1,HU Yu-hong1 |
| (1. Department of Geriatrics, Changhai Hospital, Second Military Medical University, Shanghai 200433,China;2. Department of Geratology,Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu, China) |
| Abstract: |
| ObjectiveTo investigate the relationship between sleep quality and mild cognitive impairment(MCI) in elderly patients with type 2 diabetes mellitus(T2DM).MethodsWe collected 97 elderly patients with type 2 diabetes mellitus and divided them into two groups: MCI group (DM-MIC) and normal cognition group (DM-NC group). All subjects were evaluated with cognition scores of Mini-mental state examination (MMSE), Montreal Cognitive Assessment (MOCA),Self-Rating Anxiety Scale(SAS),Center for Epidemiogical Studies Depression Scale(CES-D), Activity of daily living(ADL), Global Deterioration Scale(GDS), and Pittsburgh sleep quality index(PSQI). Independent t-test and Spearman’s rank correlation analysis were performed.ResultsThe hypnotic use in DM-MCI group was significantly more than that in DM-NC group (P=0.046), and it had a negative correlation with the score of delayed recall, but not statistically significant(r=-0.277, P=0.062). Significantly negative correlations were also found between the score of PSQI and MOCA (r=-0.362), PSQI and attention(r=-0.319), PSQI and delayed recall(r=-0.409), daytime dysfunction and MOCA(r=-0.393), daytime dysfunction and abstraction(r=-0.337), night sleep disorders and language(r=-0.439), sleep efficiency and delayed recall(r=-0.325), and subjective sleep quality and delayed recall(r=-0.336) in DM-MCI group(P<0.05).ConclusionSleep quality is correlated with some symptoms of mild cognitive impairment in elderly patients with T2DM. |
| Key words: aged type 2 diabetes mellitus sleep quality cognition disorders |
