| 摘要: |
| 目的探讨肠外营养(TPN)与肠内营养(EN)联合应用对重症急性胰腺炎(SAP)的影响。方法126例重症急性胰腺炎患者分为3组：TPN组(n=42)行全胃肠外营养治疗；TPN+EN组(n=42)先行TPN,再过渡为PN+EN,最后EN；EN组(n=42)行肠内营养治疗。肠内营养选短肽型制剂,通过空肠造瘘管或鼻空肠管给予,观察3组临床指标变化。结果治疗前,3组APACHE Ⅱ评分、Ranson评分和C-反应蛋白浓度差异无统计学差异；治疗后,TPN组血总胆红素明显升高(P<0.05),而治愈率、病死率、血浆白蛋 |
| 关键词: 全胃肠外营养 肠内营养 急性重症胰腺炎 营养疗法 |
| DOI：10.3724/SP.J.1008.2011.0737 |
| 投稿时间：2011-04-09修订日期：2011-06-06 |
| 基金项目: |
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| Total parenteral nutrition combined with enteral nutrition in treatment of severe acute pancreatitis |
| ZHANG Yong-sheng1△,SHU Xiao-liang2△*,ZHONG Jing-xia2,SHENG Ying2,MENG Bei-lei2 |
| (MENG Bei-lei2;2. Department of Nutrition, Tongji Hospital ,Tongji University,Shanghai 200065,China) |
| Abstract: |
| ［Abstract］ Objectives: To explore the effect of the combined application of total parenteral nutrition(TPN)and enteral nutrition (EN) in severe acute pancreatitis（SAP）. Methods One hundred and twenty-six patients with SAP were randomized either to treat with TPN support(TPN group, n=42)or with EN support(EN group, n=42) and with TPN+ EN support(TPN+ EN group, n=42) ,Peptisorb type of enteral nutrition were chosen during the jejunal nutrition ，The chang of clin data were observed. Results During observation, APACHE-Ⅱ scores, Ranson score, the curative rate, the mortality rate and the nutritional state of body There were no significantly differences in 3 group befere nutritional support（P>0.05）. The incidences of complications and the average hospital stay significantly decreased in TPN+EN group after treatment compared with TPN group and EN group. The incidences of complications were significantly lower than those in EN group after treatment Compared with TPN（P<0.05）. Conclusions: The combined application of total parenteral nutrition(TPN)and enteral nutrition (EN) can effectively reduced the incidences of complications, the average hospital stay and improve the nutrition conditions in （SAP）.Therefore ,it provides the most reasonable way in nutrition therapy of SAP. |
| Key words: Total parenteral nutrition Enteral nutrition Severe acute pancreatitis Average Length of time Complication |
