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2型糖尿病患者抑郁情绪与糖化血红蛋白、血脂及其应对方式的研究
牛徐林1,2,张建新1*
0
(1. 中国科学院心理研究所中国科学院研究生院,北京,100101
2. 首都医科大学附属复兴医院教育处,北京 100045
*通信作者)
摘要:
目的 探讨2型糖尿病患者抑郁情绪与糖化血红蛋白、血脂及其应对方式的关系。方法 根据Zung抑郁自评量表(Self-Rating Depression Scale, SDS)测定结果 将73例2型糖尿病患者分为抑郁情绪组(n=31)和无抑郁情绪组(n=42),采用Zung焦虑自评量表(Self-Rating Anxiety Scale, SAS)进行验证考察。采用医学应对方式问卷(Medical Coping Modes Questionnaire,MCMQ)评定两组患者对疾病的应对方式,并比较两组患者糖化血红蛋白(HbA1c)、甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平的差异。结果 2型糖尿病有抑郁情绪组SAS标准分、MCMQ中屈服(resignation)方式分值高于无抑郁情绪组(P<0.01),而两组间HbA1c、血脂水平及面对(confronce)、回避(avoidance)方式分值的差异均无统计学意义。结论 使用屈服应对方式的2型糖尿病患者更易合并抑郁情绪。
关键词:  2型糖尿病  抑郁  糖化血红蛋白;脂类;应对行为
DOI:10.3724/SP.J.1008.2012.00685
投稿时间:2011-10-12修订日期:2012-04-09
基金项目:
Association of depression with glycosylated hemoglobin,lipid metabolism and coping style in patients with type 2 diabetes mellitus
NIU Xu-lin1,2,ZHANG Jian-xin1*
(1. Institute of Psychology, Chinese Academy of Sciences,Graduate University of Chinese Academy of Sciences, Beijing 100101, China
2. Department of Education, Fuxing Hospital, Capital Medical University, Beijing 100045, China
*Corresponding author.)
Abstract:
Objective To investigate the association of depression with glycosylated hemoglobin, lipid metabolism and coping style in patients with type 2 diabetes mellitus (DM). Methods A total of 73 patients with type 2 DM were divided into depression group (n=31) and non-depression group (n=42) according to the Results of Zung Self-Rating Depression Scale. The anxiety statuses were evaluated by Zung Self-Rating Anxiety Scale(SAS). The coping style was assessed by Medical Coping Modes Questionnaire (MCMQ). Moreover, the blood HbA1c, triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), and low density lipoprotein cholesterol (LDL-C) were also compared between the two groups. Results The SAS standard score and MCMQ score of resignation in the depression group were significantly higher than those in the non-depression group (P<0.01). The MCMQ score of confronce and avoidance, blood HbA1c, TG, TC, HDL-C, and LDL-C were not significantly different between the 2 groups. Conclusion It is suggested that type 2 DM patients with resignation coping style are more liable to have depression.
Key words:  type 2 diabetes mellitus  depression  glycosylated hemoglobin  lipids  lipoproteins  coping behavior