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药物洗脱支架治疗症状性椎动脉开口狭窄
卢海涛1,张文川1,黄清海2,刘建民2*
0
(1. 上海交通大学医学院附属新华医院崇明分院神经外科,上海 202150
2. 第二军医大学长海医院神经外科,上海 200433
*通信作者)
摘要:
目的探讨药物洗脱支架辅助血管成形术治疗症状性椎动脉开口狭窄的手术安全性及近期疗效。方法从2004年6月至2008年6月,采用药物洗脱支架对24例因椎动脉开口狭窄引发脑卒中或短暂性脑缺血发作的患者行血管成形术,并分析患者影像学资料、围手术期并发症和临床随访结果。结果所有患者手术均成功,术后狭窄明显改善,平均随访时间(19±2)个月,2例有轻度的支架内再狭窄。结论药物洗脱支架治疗症状性椎动脉开口狭窄安全、可行,短期疗效满意。
关键词:  脑缺血  椎动脉  血管成形术  支架
DOI:10.3724/SP.J.1008.2012.00893
投稿时间:2012-02-29修订日期:2012-05-16
基金项目:
Drug-eluting stent for treatment of symptomatic vertebral artery origin stenosis
LU Hai-tao1,ZHANG Wen-chuan1,HUANG Qing-hai2,LIU Jian-min2*
(1. Department of Neurosurgery,Xinhua Hospital Chongming Branch, Shanghai Jiaotong University School of Medicine, Shanghai 202150, China
2. Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
*Corresponding author.)
Abstract:
ObjectiveTo investigate the safety, early and mid-term outcomes of drug-eluting stent-assisted angioplasty in treating symptomatic vertebral artery origin stenosis. MethodsFrom June 2004 to June 2008 a total of 24 patients with stroke or transient ischemic attack (TIA) due to vertebral artery (VA) origin atherosclerotic stenosis received drug-eluting stent-assisted angioplasty. Patient records were reviewed for angiographic findings, peri-procedural complications, and follow-up data. ResultsThe procedures were technically successful for all patients and the stenoses were greatly improved. All patients were available for follow-up for (19±2) months. Two patients developed mild in-stent restenosis. ConclusionOur finding confirms that drug-eluting stent-assisted angioplasty is feasible and safe for treating symptomatic vertebral artery origin stenosis, with satisfactory early outcome.
Key words:  brain ischemia  vertebral artery  angioplasty  stents