| 摘要: |
| 目的 调查血压正常的中年人群的盐敏感状况,比较慢性盐负荷试验与冷加压试验两种方法在盐敏感性检出上的一致性。 方法 对68例血压正常的中年人进行冷加压试验和慢性盐负荷试验,根据慢性盐负荷试验结果将该人群分为盐敏感(SS)组和盐不敏感(NSS)组,比较SS组和NSS组的一般资料及血压增幅值差异。采用配对四格表资料的χ2 检验比较慢性盐负荷试验和冷加压试验两种方法检测盐敏感性的差异。 结果 慢性盐负荷试验结果发现,SS组为22例(32.4%),NSS组为46例(67.6%)。与NSS组相比,SS组的年龄偏大、高血压家族史比例偏高(P<0.05),静息时心率、收缩压、舒张压均偏高(P<0.01)。与NSS组比较,SS组在冷加压试验后舒张压、收缩压、平均动脉压增幅均升高(P<0.05,P<0.01)。慢性盐负荷试验和冷加压试验两种方法检测盐敏感性的结果差异无统计学意义(χ2=0.363,P＞0.05)。结论 血压正常的中年人群中盐敏感性检出率为32.4%，冷加压试验或可代替慢性盐负荷试验检测人群的盐敏感性。 |
| 关键词: 盐敏感 盐负荷试验 冷加压试验 血压 |
| DOI：10.3724/SP.J.1008.2012.00747 |
| 投稿时间：2012-03-31修订日期：2012-05-18 |
| 基金项目: |
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| Salt sensitivity in middle-aged population with normal blood pressure and method for determining salt sensitivity |
| HAN Fei-zhou, WANG Zheng, DING Yan-ping, WANG Qian, LIN Hong-ling |
| (No.2 Department of Sanatorium, The Sanatorium of PLA Nanjing Military Area Command, Hangzhou 310007, Zhejiang, China) |
| Abstract: |
| ObjectiveTo investigate the salt sensitivity of middle-aged population with normal blood pressure, and to observe the consistency of chronic sodium load test and cold pressor test in determining salt sensitivity. MethodsTotally 68 middle-aged volunteers with normal blood pressure were divided into salt sensitivity (SS) group and non-salt sensitivity (NSS) group according to the results of chronic sodium load test, and the general data and increase amplitudes of blood pressure were compared between SS and NSS groups. The results of the two tests were compared by χ2 test of fourfold table. ResultsAccording to the results of chronic sodium load test 22 (32.4%) subjects were included in the SS group and 46 (67.6%) were included in the NSS group. Compared with NSS group, SS group had a significantly elder age, higher proportion of family hypertension history (P<0.05),and significantly higher heart rate, systolic blood pressure (SBP), and diastolic blood pressure (DBP) at rest (P<0.01). After cold pressor test, the increase amplitudes of SBP, DBP and mean artery pressure(MAP) in SS group were significantly higher than those in NSS group (P<0.05, P<0.01). χ2 test of fourfold table showed no significant difference between sodium load test and cold pressor test in determining salt sensitivity (χ2=0.363, P＞0.05). ConclusionThe rate of salt sensitivity in the present normotensive middle-aged population is 32.4%. Cold pressor test may be used as a substitute for the chronic sodium load test in determination of salt sensitivity. |
| Key words: salt sensitivity sodium load test cold pressor test blood pressure |
