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软组织透明细胞肉瘤18F-FDG PET/CT影像学特征分析
白楚杰1,方志伟1*,李丽琴2,陈静1,李舒1
0
(1.北京大学肿瘤医院暨北京市肿瘤防治研究所骨与软组织肿瘤科,恶性肿瘤发病机制及转化研究教育部重点实验室,北京 100142
2.中国人民解放军第二炮兵总医院肿瘤放射诊疗中心,北京 100086
*通信作者)
摘要:
目的探讨软组织透明细胞肉瘤的PET/CT特征。方法10例经病理证实的透明细胞肉瘤术前均行18F-FDG PET/CT检查,对肿瘤影像学表现及临床特征进行分析。结果10例患者原发病灶的最大标准化摄取值(SUVmax)平均值为6.52(5~9.6)。PET/CT发现肺转移7例,软组织转移5例,区域淋巴结转移3例,未发现骨、肝、脑转移;而相应的CT检查发现肺转移6例,软组织转移1例。结论软组织透明细胞肉瘤的18F-FDG PET/CT影像缺乏特异性,但可以更好地显示病变范围及转移情况,使分期更加准确、及时,有利于选择针对性的治疗方案。
关键词:  透明细胞肉瘤  正电子发射断层显像术  X线计算机体层摄影术  诊断
DOI:10.3724/SP.J.1008.2012.001344
投稿时间:2012-11-10修订日期:2012-12-12
基金项目:
18F-FDG PET/CT image analysis of clear cell sarcoma of soft tissue
BAI Chu-jie1,FANG Zhi-wei1*,LI Li-qin2,CHEN Jing1,LI Shu1
(1. Department of Bone and Soft Tissue Oncology, Key Laboratory of Carcinogenesis and Translational Research of Ministry of Education, Cancer Hospital & Institute of Peking University, Beijing 100142, China
2. Center of Oncology Diagnosis and Radiotherapy, General Hospital of the Second Artillery Force of Chinese PLA, Beijing 100086, China
*Corresponding author.)
Abstract:
ObjectiveTo investigate the 18F-FDG PET/CT features of clear cell sarcoma (CCS) of soft tissue. MethodsTen patients with pathologically confirmed CCS were enrolled in the present study. All patients underwent preoperative 18F-FDG PET/CT scanning, and the image findings and clinical characteristics of the tumors were analyzed. ResultsThe mean maximum standard uptake value (SUVmax) of the primary lesions was 6.52(range, 5-9.6) in the patients. PET/CT revealed lung metastasis in 7 patients, soft tissue metastases in 5, and regional lymph node metastases in 3, with no brain/bone/liver metastases. CT findings showed lung metastases in 6 cases and soft tissue metastasis in one. ConclusionCCS 18F-FDG PET/CT image lacks specificity, but it can better demonstrate the extent and metastases of CCS, helping the accurate, timely, and more targeted therapy.
Key words:  clear cell sarcoma  positron-emission tomography  X-ray computed tomography  diagnosis