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112例青年胃癌的临床病理特点及预后分析
徐健,罗天航,申晓军,魏国,马立业,薛绪潮,聂明明*,毕建威
0
(第二军医大学长海医院普通外科,上海 200433
*通信作者)
摘要:
目的 分析青年胃癌的临床病理特点及生存时间、预后影响因素。方法 对我院2000年1月1日至2005年12月31日间收治的1135例患者资料按年龄分为青、老年组,分别对性别、年龄、病理特点、生存时间、预后影响因素进行统计分析。结果 青年组胃癌女性发病率相对较高,弥散型胃癌多见,好发于胃中下部。而在肿瘤分期、生存情况上,与老年组均无明显统计学差异(P<0.05)。肿瘤分期、淋巴转移个数为影响青年胃癌患者预后的独立危险因素。结论 青年胃癌在临床病理特点与预后与老年胃癌无明显差异,对于青年胃癌仍应采取积极、规范的治疗。
关键词:  胃肿瘤  青年  病理学  预后
DOI:
投稿时间:2013-02-25修订日期:2013-07-01
基金项目:
Gastric cancer in 112 young patients: clinicopathological characteristics and prognostic analysis
XU Jian,LUO Tian-hang,SHEN Xiao-jun,WEI Guo,MA Li-ye,XUE Xu-chao,NIE Ming-ming*,BI Jian-wei
(Department of General Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China*Corresponding author.)
Abstract:
Objective: To study the clinicopathologic characteristics, survival time and prognostic factors of gastric cancer(GC) in young patients. Methods: The authors studied 1135 patients with GC who received curative resections. They were classified into two groups: those aged 40 years or less (young); and those aged more than 41 years (elderly). Clinicopathologic characteristics, survival rates and prognostic factors were analyzed. Results: Young patients were predominately female, had more diffuse type, and had lower proportion of tumors in the upper third of the stomach. However, survival rate was not significantly different between the two groups. TNM stage, number of lymph node metastasis were independent negative prognostic factors in young patients. Conclusions: GC in young patients demonstrates only minor deviations from the older with a similar survival rate, which suggests positive and standard treatment should be taken to young patients with GC.
Key words:  stomach neoplasms  young patient  pathology  prognosis