| 摘要: |
| 目的 探讨超声实时组织弹性成像（real-time tissue elastography，RTE）在肝脏局灶性结节性增生（focal nodular hyperplasia，FNH）与肝腺瘤（hepatocellular adenoma，HCA）鉴别诊断中的应用价值。方法 回顾性分析经术后病理证实的20例FNH（22个病灶）和8例HCA（9个病灶）患者的超声RTE检查资料，采用5分法对弹性图像进行评分并测量其应变率比值（strain ratio，SR），比较FNH和HCA弹性图像评分和SR的差异。结果 FNH弹性图像评分以3～4分为主（18/22，81.8%），而HCA评分以1分为主（5/9，55.6%），两者的评分差异存在统计学意义（P=0.0002）； FNH和HCA的应变率比值分别为7.47±4.53、1.64±0.88，差异具有统计学意义（P<0.000 1）。结论 超声RTE显示FNH硬度明显高于HCA，是对常规超声的有力补充，有助于两者的鉴别诊断。 |
| 关键词: 超声检查 弹性成像技术 肝疾病局限性结节状增生 腺瘤 |
| DOI：10.3724/SP.J.1008.2014.00524 |
| 投稿时间：2013-12-03修订日期：2014-04-29 |
| 基金项目:上海市科委医学重点发展基金（10411951900）. |
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| Value of real-time tissue elastography in differential diagnosis of focal nodular hyperplasia and hepatocellular adenoma |
| HONG Jun-feng1,GUO Jia1*,LIANG Li-qiong1,JI Jian-feng2 |
(1. Department of Ultrasonography, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 200438, China;
2. Department of Ultrasonography, No. 94 Hospital of PLA, Nanchang 330002, Jiangxi, China
*Corresponding authors.) |
| Abstract: |
| Objective To investigate the value of real-time tissue elastography (RTE) in the differential diagnosis of focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA). Methods The RTE data of 20 patients with pathologically proven FNH (22 lesions) and 8 patients with HCA (9 lesions) were retrospectively analyzed. The RTE data were evaluated by scores(grades 1-5)and the strain ratios (SR) of the nodules were calculated and compared between the two groups. Results Most FNH lesions had a grade of 3-4(18/22,81.8%)on elastography, while most lesions of HCA had a grade of 1(5/9,55.6%)on elastography, with significant difference found between the two groups (P=0.000 2). The strain ratio of FNH was significantly higher than that of HCA(7.47±4.53 vs 1.64±0.88, P<0.000 1). Conclusion The stiffness of FNH in RTE is notably higher than that of HCA, indicating RTE may be a supplementary to routine ultrasonic examination, which may be helpful for differential diagnosis of FNH and HCA. |
| Key words: ultrasonography elasticity imaging techniques liver diseases focal nodular hyperplasia adenoma |
