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运动和代谢综合征
顾庆1,2,刘志民1*
0
(1. 第二军医大学长征医院内分泌科, 上海 200003;
2. 上海市市东医院内分泌科, 上海 200438
*通信作者)
摘要:
代谢综合征是一组以中心性肥胖、高血糖、血脂异常以及高血压等聚集发病,严重影响机体健康的临床症候群,而运动对代谢综合征有良好的预防和治疗作用,运动可以减轻体质量,改善内脏脂肪堆积;提高胰岛素敏感性,提高葡萄糖转运蛋白4的水平,促进骨骼肌利用葡萄糖从而降低血糖;改善血管内皮功能,增加一氧化氮分泌,减少血管内皮素分泌,降低血压;降低血浆三酰甘油及低密度脂蛋白胆固醇,升高高密度脂蛋白胆固醇。本文综述了运动对于代谢综合征各个方面的影响。
关键词:  运动  代谢综合征  肥胖症  血糖  高血压  血脂异常
DOI:10.3724/SP.J.1008.2015.00434
投稿时间:2014-08-14修订日期:2015-01-24
基金项目:杨浦区卫生和计划生育委员会青年科研课题(201306).Supported by Youth Foundation of Yangpu Distrct Health &Family Planning Commission
Exercise and metabolic syndrome
GU Qing1,2,LIU Zhi-min1*
(1. Department of Endocrinology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China;
2. Department of Endocrinology, Shanghai Shidong Hospital, Shanghai 200438, China
*Corresponding author)
Abstract:
Metabolic syndrome is characterized by simultaneous occurrence of central obesity, hyperglycemia, dyslipidemia and hypertension, posing a serious health problem. Exercise plays a pivotal role in preventing and treating metabolic syndrome: it can (1)reduce weight and improve the fat deposit in organs; (2) improve insulin sensitivity and glucose transporter4 level and down-regulate blood glucose by promoting muscle glucose utilization; (3) improve the vascular endothelial function, increase the secretion of nitric oxide, decrease the secretion of endothelin, and finally reduce blood pressure; and (4)decrease blood levels of triglyceride and low density lipoprotein cholesterol, and increase the level of high density lipoprotein cholesterol. This paper is to review the effect of exercise on metabolic syndrome in an all around manner.
Key words:  exercise  metabolic syndrome  obesity  blood glucose  hypertension  dyslipidemia