| 摘要: |
| 近年来越来越多的研究发现癫痫患者存在一种新型的遗忘形式——快速的长时遗忘（ALF），即初始的学习和记忆正常，但会在随后的几天或几周出现异常。虽然ALF从发现至今已经近30年，但仍有很多问题不明确。本文就ALF定义、神经生物学基础、影响因素、在其他疾病中的研究、目前文献中的评定方法进行综述。 |
| 关键词: 快速的长时遗忘 癫痫 发作 神经生物学 |
| DOI：10.16781/j.0258-879x.2021.01.0071 |
| 投稿时间：2020-02-06修订日期：2020-05-11 |
| 基金项目: |
|
| Accelerated long-term forgetting in epilepsy: recent progress |
| CHAI Chang-feng,ZHANG Xiu-tian,BI Xiao-ying* |
(Department of Neurology, Changhai Hospital, Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| In recent years many studies have found that epilepsy patients had a new form of forgetting-accelerated long-term forgetting (ALF), with normal initial learning and memory, becoming abnormal in the following days or weeks. Although it has been nearly 30 years since ALF's discovery, there are still many problems to be understood. This paper reviews the definition, neurobiological basis, influencing factors, involvement in other diseases and current evaluation methods of ALF. |
| Key words: accelerated long-term forgetting epilepsy seizures neurobiology |
