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Ⅱ型减压病肺损伤的治疗进展
曹曦元,赵松韵,董宇超,白冲*
0
(海军军医大学(第二军医大学)第一附属医院呼吸与危重症医学科, 上海 200433
*通信作者)
摘要:
随着我国海防事业的不断发展及水下领域探索深度的不断加深,水下作业不断增加,与潜水密切相关的减压病日益增多。减压病分为Ⅰ型(轻型)和Ⅱ型(重型)2种类型,其中Ⅱ型减压病损伤人体多个器官功能,患者病情严重。Ⅱ型减压病肺损伤最终会发展为呼吸衰竭,是导致潜水员死亡的重要原因,更是治疗的重点内容。本文对Ⅱ型减压病肺损伤的病理生理过程及当前国内外该病的临床治疗措施与研究进展进行综述。
关键词:  Ⅱ型减压病  肺损伤  高压氧  肺表面活性物质
DOI:10.16781/j.CN31-2187/R.20200164
投稿时间:2020-02-12修订日期:2021-12-16
基金项目:
Progress in treatment of lung injuries induced by type Ⅱ decompression sickness
CAO Xi-yuan,ZHAO Song-yun,DONG Yu-chao,BAI Chong*
(Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
With the development of China's marine defense and the increased depth of the underwater exploration, the diving-related decompression sicknesses are increasing, and they can be divided into type Ⅰ (mild) and type Ⅱ (severe) decompression sicknesses. Type Ⅱ decompression sickness can damage the function of multiple organs, leading to more serious condition. The lung injuries induced by type Ⅱ decompression sickness may eventually progress to respiratory failure, which is not only an important cause of death, but also the key of the treatment. Based on the pathophysiological process of lung injuries induced by type Ⅱ decompression sickness, this paper summarizes the current clinical treatments and research progress at home and abroad.
Key words:  type Ⅱ decompression sickness  lung injuries  hyperbaric oxygenation  pulmonary surfactant