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治疗性低温用于急性缺血性脑卒中的研究进展
花伟龙,张磊,李翯,刘鹏,张永鑫,李子付,沈红健,邢鹏飞,张永巍,洪波,杨鹏飞*,刘建民
0
(海军军医大学(第二军医大学)长海医院脑血管病中心, 上海 200433
*通信作者)
摘要:
血管内治疗是急性大血管闭塞性缺血性脑卒中的标准治疗方法之一,然而即使血管成功再通,仍有一部分患者预后不良。治疗性低温是目前极具研究价值的神经保护方法,其有显著改善患者预后的潜力,但疗效尚不确切。本文就治疗性低温用于急性缺血性脑卒中的研究进展进行综述。
关键词:  缺血性脑卒中  血管内治疗  治疗性低温  神经保护
DOI:10.16781/j.0258-879x.2021.02.0171
投稿时间:2020-10-08修订日期:2020-12-18
基金项目:上海市卫生和计划生育委员会智慧医疗专项研究项目(2018ZHYL0218).
Therapeutic hypothermia in treatment of acute ischemic stroke: an advance
HUA Wei-long,ZHANG Lei,LI He,LIU Peng,ZHANG Yong-xin,LI Zi-fu,SHEN Hong-jian,XING Peng-fei,ZHANG Yong-wei,HONG Bo,YANG Peng-fei*,LIU Jian-min
(Stroke center, Changhai Hospital, Naval Medical University (Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
Endovascular treatment is one of the standard treatments for acute large vessel occlusive ischemic stroke. However, a considerable number of patients still have poor outcomes, even if they achieved successful reperfusion. Therapeutic hypothermia is an attractive neuroprotective method and has a potential to significantly improve patient prognosis, despite its uncertain efcacy. This review sums up the research progress of therapeutic hypothermia in the treatment of acute ischemic stroke.
Key words:  ischemic stroke  endovascular treatment  therapeutic hypothermia  neuroprotection