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无创颅内压监测技术研究进展
武蒙蒙,胡红建,梅其勇*
0
(海军军医大学(第二军医大学)长征医院神经外科, 上海 200003
*通信作者)
摘要:
颅内压的变化能够及时、准确地提示颅内生理病理变化情况,科学合理的颅内压监测能够为预防和治疗颅脑疾病提供有效的依据。现有的颅内压监测方法主要分为有创的颅内压监测和无创的颅内压监测2种。有创的颅内压监测方法因其高精确度一直被视为金标准,但同时也因其费用高、并发症多而限制了其适用范围。为追求一种廉价、可靠、适用范围广且并发症少的颅内压监测方法,近年来不断有科研工作者及临床工作者对各种无创的颅内压监测方法进行研究和探索。本文对近年来多种无创颅内压监测的方法、原理、现状、相关产品的优缺点及研究新动向进行简要综述。
关键词:  无创颅内压监测  经颅多普勒超声检查  闪光视觉诱发电位  双深度经眼眶多普勒超声检查  视神经鞘直径  鼓膜位移  耳声发射
DOI:10.16781/j.0258-879x.2021.08.0897
投稿时间:2021-03-02修订日期:2021-04-30
基金项目:装备军内科研项目重点专项(HJ20191A020094).
Noninvasive intracranial pressure monitoring technology: research progress
WU Meng-meng,HU Hong-jian,MEI Qi-yong*
(Department of Neurosurgery, Changzheng Hospital, Naval Medical University(Second Military Medical University), Shanghai 200003, China
*Corresponding author)
Abstract:
The changes in intracranial pressure can timely and accurately indicate the physiological and pathological changes. Therefore, scientific and reasonable intracranial pressure monitoring can provide an effective basis for the prevention and treatment of craniocerebral diseases. Two main methods for intracranial pressure monitoring are invasive intracranial pressure monitoring and noninvasive intracranial pressure monitoring. Invasive intracranial pressure monitoring has been regarded as the golden standard due to its high accuracy, but its application is limited for its high cost and many complications. To seek a cheap, reliable, widely applicable intracranial pressure monitoring method with few complications, scientific researchers and clinical workers have worked hard for various noninvasive intracranial pressure monitoring methods. This paper briefly reviews the methods, mechanisms, current situation, advantages and disadvantages of related products and research trends of many noninvasive intracranial pressure monitoring ways developed in recent years.
Key words:  noninvasive intracranial pressure monitoring  transcranial Doppler ultrasonography  flash visual evoked potential  two-depth transorbital Doppler ultrasonography  optic nerve sheath diameter  tympanic membrane displacement  otoacoustic emission