摘要: |
新型冠状病毒肺炎(COVID-19)除损伤呼吸系统外,还可累及神经系统,甚至造成严重的临床后果。本文从致病机制、临床症状及治疗预后3个方面阐述了严重急性呼吸综合征冠状病毒2(SARS-CoV-2)对神经系统损伤的研究现状,系统性归纳了COVID-19神经系统病变的病理机制,为COVID-19的诊断和治疗提供新思路。 |
关键词: 严重急性呼吸综合征冠状病毒2 病理机制 神经系统损害 临床特征 诊断 治疗 |
DOI:10.16781/j.CN31-2187/R.20210777 |
投稿时间:2021-08-09修订日期:2021-09-29 |
基金项目:国家自然科学基金(81872072). |
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Nervous system injury caused by severe acute respiratory syndrome coronavirus 2:research status |
MA Pei-pei1,HONG Fan1,XU Tao1,CHEN Ju-xiang2* |
(1. Department of Neurosurgery, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China; 2. Department of Neurosurgery, The First Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200433, China *Corresponding author) |
Abstract: |
In addition to damaging the respiratory system, coronavirus disease 2019 (COVID-19) can also affect the nervous system, and even cause serious clinical consequences. This paper expounds the research status of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on nervous system injury from 3 aspects: pathogenesis, clinical symptoms and treatment prognosis, and systematically summarizes the pathological mechanism of nervous system lesions caused by COVID-19, hoping to provide new ideas for the diagnosis and treatment of COVID-19. |
Key words: severe acute respiratory syndrome coronavirus 2 pathological mechanism nervous system damage clinical features diagnosis therapy |