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左心耳电隔离在心房颤动治疗中的研究进展
刘超,赵海娟,赵腾,郭志福*
0
(海军军医大学(第二军医大学)第一附属医院心血管内科, 上海 200433
*通信作者)
摘要:
近年来,多项研究证实左心耳与心房颤动的触发及维持密切相关,且左心耳电隔离(LAAEI)策略可有效改善心房颤动消融治疗的预后,减少心房颤动复发。目前LAAEI主要通过射频消融或冷冻球囊消融、外科干预、LARIAT装置结扎等策略实现,但加深对其并发症的认识很有必要,尤其是术后潜在的血栓事件或卒中。本文主要就左心耳的解剖学特征及LAAEI的临床治疗进展、相关并发症作一综述。
关键词:  左心耳电隔离  心房颤动  射频消融术  血栓事件  卒中
DOI:10.16781/j.CN31-2187/R.20211114
投稿时间:2021-11-03修订日期:2021-12-15
基金项目:国家自然科学基金(81970278).
Left atrial appendage electrical isolation in the treatment of atrial fibrillation: research progress
LIU Chao,ZHAO Hai-juan,ZHAO Teng,GUO Zhi-fu*
(Department of Cardiovasology, The First Affiliated Hospital of Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
In recent years, several studies have demonstrated that the left atrial appendage is closely related to the induction and maintenance of atrial fibrillation, and the left atrial appendage electrical isolation (LAAEI) has been confirmed to effectively improve the success rate of atrial fibrillation ablation and reduce the recurrence of atrial fibrillation. Currently, LAAEI is mainly achieved through radiofrequency or cryoballoon ablation, surgical intervention, LARIAT ligation, etc. However, it is necessary to promote the understanding of its complications, especially the postoperative thrombus events and stroke. This paper reviews the anatomical characteristics of left atrial appendage, as well as the clinical treatment progress and related complications of LAAEI.
Key words:  left atrial appendage electrical isolation  atrial fibrillation  radiofrequency ablation  thrombus events  stroke