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子宫内膜异位症非介入性诊断研究进展
武润哲,俞超芹*
0
(海军军医大学(第二军医大学)中医系, 上海 200433
*通信作者)
摘要:
本文综述了子宫内膜异位症非介入性诊断研究的新进展,包括血清标志物,组织生物标志物,基因/蛋白质组学及光谱分析筛查方法,诊断评分体系与算法模型的应用,影像学检查中图像参数、新技术、新操作技巧在诊断方面的应用,并分析了其诊断效能、临床应用可行性及不足。基于目前子宫内膜异位症诊断研究状况,认为完善的诊断评分体系建立有利于快速初步分诊,多标志物组合的算法分析有利于准确诊断,影像学检查新技术的应用有利于提高诊断灵敏度及鉴别诊断能力。
关键词:  子宫内膜异位症  血清标志物  量表  诊断模型  影像学检查
DOI:10.16781/j.CN31-2187/R.20211128
投稿时间:2021-11-07修订日期:2022-03-29
基金项目:国家自然科学基金(82074206,81774352),上海市进一步加快中医药事业发展三年行动计划[ZY(2018-2020)-FWTX-1107].
Non-interventional diagnosis of endometriosis: research progress
WU Run-zhe,YU Chao-qin*
(School of Traditional Chinese Medicine, Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
This article reviewed recent progress in non-interventional diagnosis of endometriosis, including serum and tissue markers, screening methods with genomics/proteomics and spectrum analysis, application of diagnostic scoring system and algorithm model, application of image parameters, new technologies and new operation skills in imaging diagnosis. The diagnostic efficacy, clinical feasibility and disadvantage were analyzed. Based on the current research status of endometriosis diagnosis, it is believed that a better diagnosis scoring system can provide evidence for rapid differential diagnosis, diagnostic algorithm based on multiple markers can promote diagnosis accuracy, and new imaging technologies can improve the diagnostic sensitivity and differential diagnostic ability.
Key words:  endometriosis  serum markers  scale  diagnostic model  imaging examination