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| 超声引导下腮腺良性肿瘤的微波消融治疗 |
| 章建全1,2*,闫磊3,滕学东4,陈红琼1,程杰1,钱桂荣5,纪荣明6 |
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(1. 上海国际医学中心介入超声科, 上海 201318;
2. 海军军医大学(第二军医大学)第二附属医院超声诊断科, 上海 200003;
3. 中国人民解放军联勤保障部队第九〇四医院苏州医疗区特诊科, 苏州 215007;
4. 烟台万华医院超声科, 烟台 264012;
5. 苏州永鼎医院超声医学科, 苏州 215200;
6. 海军军医大学(第二军医大学)基础医学院解剖学教研室, 上海 200433
*通信作者) |
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| 摘要: |
| 目的 探讨超声引导下腮腺良性肿瘤微波消融治疗的可行性、安全性与有效性。方法 2013年7月至2021年6月对临床诊断腮腺肿物、超声诊断疑似腮腺肿瘤并实施超声引导下切割式穿刺活检、组织学病理诊断为腮腺良性肿瘤的患者行超声引导下微波消融治疗。对腮腺消融区实施动态超声影像评估，并对穿刺活检和消融治疗相关的并发症进行动态随访。结果 8年间共有13例腮腺肿瘤患者按研究设计接受超声引导下切割式穿刺活检，其中12例为良性肿瘤并接受超声引导下微波消融治疗，包括6例腮腺腺淋巴瘤、4例腮腺多形性腺瘤、1例腮腺皮样囊肿和1例腮腺淋巴组织结节样增生。12例患者年龄为10～79岁（中位年龄60.5岁），瘤体最大径为17.8～49.0 mm（中位值为26.15 mm），微波消融均一次性完成，消融时长70～598 s（中位值为155 s）。至截稿，10例患者达到痊愈，消融区完全吸收时间8～37个月（中位值为23.5个月）；消融区未见肿瘤残余，腮腺内亦未见新生肿瘤；消融后未出现严重并发症。结论 超声引导下微波消融可为腮腺良性肿瘤提供效果确切、并发症轻微的微创治疗机会。 |
| 关键词: 腮腺肿瘤 良性肿瘤 超声检查 粗针穿刺活检 微波消融 超声引导 液体隔离法 |
| DOI：10.16781/j.CN31-2187/R.20211321 |
| 投稿时间：2021-12-31修订日期：2022-03-29 |
| 基金项目:国家自然科学基金（81171436）． |
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| Ultrasound-guided microwave ablation of benign parotid gland tumors |
| ZHANG Jian-quan1,2*,YAN Lei3,TENG Xue-dong4,CHEN Hong-qiong1,CHENG Jie1,QIAN Gui-rong5,JI Rong-ming6 |
(1. Department of Interventional Ultrasound, Shanghai International Medical Center, Shanghai 201318, China;
2. Department of Ultrasound, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China;
3. Department of Special Diagnosis, No. 904 Hospital of Joint Logistics Support Force of PLA, Suzhou 215007, Jiangsu, China;
4. Department of Ultrasound, Yantai Wanhua Hospital, Yantai 264012, Shandong, China;
5. Department of Ultrasound, Suzhou Yongding Hospital, Suzhou 215200, Jiangsu, China;
6. Department of Anatomy, College of Basic Medical Sciences, Naval Medical University (Second Military Medical University), Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| Objective To explore the feasibility, safety and effectiveness of ultrasound-guided microwave ablation for benign parotid gland tumors. Methods From Jul. 2013 to Jun. 2021, ultrasound-guided core needle biopsy was performed on patients with clinically diagnosed parotid mass and suspected parotid tumor diagnosed by ultrasound. Benign parotid tumors based on the biopsy histopathology were treated by using ultrasound-guided microwave ablation. The ablated area of parotid gland was evaluated by dynamic ultrasound imaging, and complications related to needle biopsy and ablative treatment were followed up. Results A total of 13 parotid tumors underwent core needle biopsy as designed during the past 8 years. Twelve benign tumors were treated with ultrasound-guided microwave ablation, including 6 adenolymphomas, 4 polymorphic adenomas, 1 dermoid cyst, and 1 nodular lymphoid hyperplasia. The age of the 12 patients were 10-79 years old (median 60.5 years old), and the maximum diameter of the tumor was 17.8-49.0 mm (median 26.15 mm). Microwave ablation was performed all at one time with a duration of 70-598 s (median 155 s) in all patients. By the deadline of this paper, 10 patients had recovered, and the time required for complete absorption in the ablation area was 8-37 months (median 23.5 months). No residual tumor was observed in the ablation area and no neoplasm was observed in the rest parotid gland. There were no serious complications after ablation. Conclusion Ultrasound-guided microwave ablation can provide accurate and minimally invasive treatment opportunities for benign parotid tumors with mild complications. |
| Key words: parotid neoplasms benign tumor ultrasonography core needle biopsy microwave ablation ultrasound guidance hydrodissection |
