| 摘要: |
| 胰十二指肠切除术是腹部外科最大的手术之一，术后并发症发生率居高不下。胰瘘引起的出血是胰十二指肠切除术后最凶险的并发症之一，其发生与胰管直径、胰腺质地、假性动脉瘤、胰肠吻合口瘘及胆肠吻合口瘘等众多因素有关。预防和处理胰瘘出血是胰腺外科的难点，也是胰腺外科医师努力的方向。本文就胰十二指肠切除术后胰瘘出血的危险因素、防治策略现状及研究进展进行综述。 |
| 关键词: 胰十二指肠切除术 胰瘘 出血 手术后并发症 |
| DOI：10.16781/j.CN31-2187/R.20220141 |
| 投稿时间：2022-02-18修订日期：2022-09-02 |
| 基金项目:上海市医苑新星杰出青年医学人才计划(2019020),海军军医大学(第二军医大学)第一附属医院"234学科攀峰计划"(2019YXK038). |
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| Postoperative pancreatic fistula-related hemorrhage after pancreatoduodenectomy: research progress |
| MA Jing-wen,MENG Yao,CHEN Gao-qi,ZHU Zhong-fei,HU Hao,HE Tian-lin* |
(Department of Hepatobiliary, Pancreatic and Splenic Surgery, The First Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| Pancreatoduodenectomy is one of the largest surgeries in abdominal surgical field, with a high incidence of postoperative complications. Postoperative pancreatic fistula (POPF)-related hemorrhage is one of the most fatal and severe complications after pancreatoduodenectomy. The risk factors of POPF-related hemorrhage include pancreatic duct size, pancreatic texture, vascular pseudoaneurysm, pancreaticojejunostomy leak, choledochojejunostomy leak, and so on. The management and prevention are of great importance to POPF-related hemorrhage, and it is the goal that pancreatic surgeons are striving for. This review provides an overview of the risk factors, prevention and treatment strategies, and research progress of POPF-related hemorrhage after pancreatoduodenectomy. |
| Key words: pancreaticoduodenectomy pancreatic fistula hemorrhage postoperative complications |
