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| 1 050例腹膜后占位的病理诊断单中心分析 |
| 武宇轩1△,塔娜2△,杜甑衎1,屈小翔1,庚广烨1,王沈凡3,施挺3,冯翔3,陈锐3,4* |
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(1. 海军军医大学(第二军医大学)基础医学院, 上海 200433;
2. 海军军医大学(第二军医大学)第一附属医院病理科, 上海 200433;
3. 海军军医大学(第二军医大学)第一附属医院泌尿外科, 上海 200433;
4. 海军军医大学(第二军医大学)卫生勤务学系卫生统计学教研室, 上海 200433
△共同第一作者
*通信作者) |
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| 摘要: |
| 目的 总结腹膜后肿瘤的疾病谱和病理特点。方法 回顾性收集2012年1月至2021年12月海军军医大学（第二军医大学）第一附属医院冯翔医师牵头的外科团队收治的1 050例诊断为腹膜后占位/肿瘤患者的病理信息，分析各类肿瘤占比及临床和病理特征。结果 共纳入1 050例病理标本，间叶源性肿瘤407例（38.76%），其中恶性肿瘤348例（33.14%），良性肿瘤59例（5.62%）；神经源性肿瘤211例（20.10%），其中恶性肿瘤18例（1.71%），良性肿瘤193例（18.38%）；淋巴造血组织来源肿瘤127例（12.10%），其中恶性肿瘤88例（8.38%），良性肿瘤39例（3.71%）；其他原发性腹膜后肿瘤19例（1.81%）；未知来源恶性肿瘤42例（4.00%）；转移性肿瘤244例（23.24%）。在间叶源性肿瘤恶性肿瘤中，最常见的病理类型为脂肪肉瘤（178例，16.95%）、平滑肌肉瘤（54例，5.14%）。结论 在腹膜后肿瘤中，间叶源性肿瘤最为常见，同时存在较高比例的神经源性肿瘤、淋巴造血组织来源肿瘤、转移性肿瘤。 |
| 关键词: 腹膜后肿瘤 肉瘤 神经组织肿瘤 淋巴瘤 病理诊断 |
| DOI：10.16781/j.CN31-2187/R.20220646 |
| 投稿时间：2022-08-02修订日期：2022-11-14 |
| 基金项目:上海市自然科学基金面上项目（22ZR1478000），上海市青年科技启明星计划（21QA1411500），中国博士后科学基金面上项目（2020M683732）. |
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| Pathological diagnosis of retroperitoneal mass—an analysis of 1 050 cases in a single center |
| WU Yu-xuan1△,TA Na2△,DU Zeng-kan1,QU Xiao-xiang1,GENG Guang-ye1,WANG Shen-fan3,SHI Ting3,FENG Xiang3,CHEN Rui3,4* |
(1. College of Basic Medical Sciences, Naval Medical University (Second Military Medical University), Shanghai 200433, China;
2. Department of Pathology, The First Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200433, China;
3. Department of Urology, The First Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200433, China;
4. Department of Health Statistics, Faculty of Health Services, Naval Medical University (Second Military Medical University), Shanghai 200433, China
△Co-first authors.
* Corresponding author) |
| Abstract: |
| Objective To discuss the disease spectrum and pathological characteristics of retroperitoneal tumors. Methods The pathological information of 1 050 patients who were diagnosed with "retroperitoneal mass/tumor" by the surgical team led by Dr. FENG Xiang of The First Affiliated Hospital of Naval Medical University (Second Military Medical University) from Jan. 2012 to Dec. 2021 was retrospectively collected, and the proportions of various types of tumors were analyzed, as well as the clinical and pathological features. Results A total of 1 050 pathological specimens were included:407 (38.76%) tumors of mesenchymal origin, including 348 (33.14%) malignant tumors and 59 (5.62%) benign tumors; 211 (20.10%) tumors of neurogenic origin, including 18 (1.71%) malignant tumors and 193 (18.38%) benign tumors; 127 (12.10%) tumors of lymphohematopoietic origin, including 88 (8.38%) malignant tumors and 39 (3.71%) benign tumors; 19 (1.81%) other primary retroperitoneal tumors; 42 (4.00%) malignant tumors of unknown origin; and 244 (23.24%) metastatic tumors. Among the malignant tumors of mesenchymal origin, the most common pathological types were liposarcoma (178 cases, 16.95%), and leiomyosarcoma (54 cases, 5.14%). Conclusion Among retroperitoneal tumors, mesenchymal tumors are the most common, followed by neurogenic tumors, lymphoid hematopoietic tumors and metastatic tumors. |
| Key words: retroperitoneal tumor sarcoma nerve tissue neoplasms lymphoma pathologic diagnosis |
