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全球慢性胰腺炎流行病学研究进展
徐金杰1,刘雨1,2,3,胡良皞1*
0
(1. 海军军医大学(第二军医大学)第一附属医院消化内科, 上海 200433;
2. 中国人民解放军东部战区总医院消化内科, 南京 210002;
3. 海军军医大学(第二军医大学)药学系, 上海 200433
*通信作者)
摘要:
慢性胰腺炎通常表现为胰腺局部或弥漫性的进展性炎症改变,常引起持续性腹痛症状,并继发胰腺内分泌和外分泌功能不全等,已成为全球大多数国家的重点公共卫生问题。20世纪40年代至20世纪末慢性胰腺炎的发病率和患病率在全球范围内总体呈现上升趋势,2000年以后,少数发达国家慢性胰腺炎的发病率和患病率趋于平稳或呈下降趋势。本文就全球慢性胰腺炎流行病学研究现状及差异化原因进行综述。
关键词:  国际性  慢性胰腺炎  流行病学  地域差异
DOI:10.16781/j.CN31-2187/R.20220870
投稿时间:2022-11-11修订日期:2023-03-27
基金项目:国家自然科学基金(82070664,82200723),上海市曙光计划(20SG36),上海申康医院发展中心市级医院新兴前沿技术联合攻关项目(SHDC12021107).
Epidemiology of chronic pancreatitis in the world: research progress
XU Jinjie1,LIU Yu1,2,3,HU Lianghao1*
(1. Department of Gastroenterology, The First Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200433, China;
2. Department of Gastroenterology, General Hospital of PLA Eastern Theater Command, Nanjing 210002, Jiangsu, China;
3. College of Pharmacy, Naval Medical University (Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
Chronic pancreatitis is usually manifested as partial or diffuse progressive inflammation of the pancreas, frequently causing symptoms like persistent abdominal pain and secondary exocrine and endocrine pancreatic insufficiency. It has become a vital public health problem in most countries around the world. From the 1940 s to the end of the 20th century, the incidence and prevalence of chronic pancreatitis showed an overall upward trend in the world. After 2000, the incidence and prevalence of chronic pancreatitis tended to be stable or showed a downward trend in a few developed countries. This article reviews the global status of epidemiological research on chronic pancreatitis and the causes for its differentiation.
Key words:  internationality  chronic pancreatitis  epidemiology  areal differentiation