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经皮穴位电刺激治疗胃肠道疾病的机制及应用进展
宋宇豪,李天行,宁北芳*
0
(海军军医大学(第二军医大学)第二附属医院消化内科, 上海 200003
*通信作者)
摘要:
经皮穴位电刺激是在针灸和经皮神经电刺激的基础上,以经皮电极在靠近神经或与神经重叠的穴位上施加电流刺激以治疗疾病的一种方法,具有无创便携、操作简便、易于推广等特点。经皮穴位电刺激可能通过平衡自主神经功能、改善胃肠动力、调节胃肠激素和神经递质分泌等机制发挥作用,在胃食管反流病、功能性消化不良、慢性便秘、肠易激综合征、炎症性肠病等胃肠道疾病的治疗中具有巨大潜力。本文总结了经皮穴位电刺激治疗的起源及作用机制,并对其在胃肠道疾病中的应用现状和发展方向进行了阐述。
关键词:  经皮穴位电刺激  经皮神经电刺激  胃肠道疾病  神经调控  胃肠动力
DOI:10.16781/j.CN31-2187/R.20230639
投稿时间:2023-11-20修订日期:2024-02-20
基金项目:军队后勤科研重点项目(BHJ22J021),上海市卫生健康委员会临床研究面上项目(202240347),海军军医大学(第二军医大学)第二附属医院临床研究项目(2023YJBF-PY06).
Transcutaneous electrical acustimulation in treating gastrointestinal diseases: mechanism and application progress
SONG Yuhao,LI Tianxing,NING Beifang*
(Department of Gastroenterology, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China
* Corresponding author)
Abstract:
Transcutaneous electrical acustimulation is a method based on electroacupuncture and transcutaneous electrical nerve stimulation, and it treats diseases by applying current stimulation with percutaneous electrodes to specific acupoints close to or overlapping with the nerves. It is non-invasive, portable, easy to operate and popularize, and may play a role by balancing autonomic nervous function, improving gastrointestinal motility, and regulating the secretion of gastrointestinal hormones and neurotransmitters. It is expected to become a promising treatment for gastrointestinal diseases, such as gastroesophageal reflux disease, functional dyspepsia, chronic constipation, irritable bowel syndrome, and inflammatory bowel disease. This article reviews the origin and mechanism of transcutaneous electrical acustimulation, as well as its application and progression in gastrointestinal diseases.
Key words:  transcutaneous electrical acustimulation  transcutaneous electrical nerve stimulation  gastrointestinal diseases  neuromodulation  gastrointestinal motility