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| 子宫内膜异位性疾病舌象及脉象客观化指标探析 |
| 郑徐1,庄梦斐1,曾薇薇2,沈丽3,张婷婷1*,屠立平4,许家佗4,朱心怡5 |
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(1. 上海中医药大学附属岳阳中西医结合医院妇科, 上海 200437;
2. 上海中医药大学附属曙光医院妇科, 上海 200000;
3. 上海市浦东新区北蔡社区卫生服务中心中医科, 上海 201204;
4. 上海中医药大学基础医学院, 上海 201203;
5. 上海中医药大学附属岳阳中西医结合医院重症医学科, 上海 200437
*通信作者) |
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| 摘要: |
| 目的 通过数字舌诊仪及脉诊仪采集子宫内膜异位性疾病患者的舌象和脉象数据，探讨子宫内膜异位性疾病的舌象及脉象客观化指标。方法 子宫内膜异位性疾病组纳入2021年6月1日至2022年9月15日在上海中医药大学附属岳阳中西医结合医院妇科张婷婷教授门诊就诊的72例子宫内膜异位性疾病患者，正常对照组纳入上海中医药大学附属曙光医院体检中心招募的35名健康成年女性。使用上海中医药大学自行研制的TFDA-1型数字舌诊仪及PDA-1型数字脉诊仪分析2组人群舌象、脉象数据的差异。结果 子宫内膜异位性疾病组与正常对照组年龄差异无统计学意义（P＞0.05）。在舌质颜色方面，子宫内膜异位性疾病组zhiCon、zhiASM、zhiENT、zhiMEAN、zhiClrB、zhiClrI、zhiClrLa、zhiClrCb和zhiClrLb值与正常对照组比较差异有统计学意义（均P＜0.05），zhiClrR、zhiClrG、zhiClrS、zhiClrL、zhiClrY和zhiClrCr值与正常对照组比较差异无统计学意义（均P＞0.05）；在舌苔颜色方面，子宫内膜异位性疾病组taiClrR、taiClrB、taiClrI、taiClrS、taiClrLa、taiClrLb、taiClrCr和taiClrCb值与正常对照组比较差异有统计学意义（均P＜0.05），taiClrG、taiClrL和taiClrY值与正常对照组比较差异无统计学意义（均P＞0.05）；在舌苔质地及厚薄方面，子宫内膜异位性疾病组perAll、perPart、taiCon、taiASM、taiENT、taiMEAN值与正常对照组比较差异均无统计学意义（均P＞0.05）。在脉象方面，子宫内膜异位性疾病组h3、h4、h5、t4、h3/h1和h4/h1值与正常对照组比较差异有统计学意义（均P＜0.05），h1、t、t1和t5值与正常对照组比较差异无统计学意义（均P＞0.05）。结论 舌象和脉象参数在子宫内膜异位性疾病患者与健康成年女性之间存在显著差异，为进一步研究子宫内膜异位性疾病的病机变化及临床辨证提供了客观化指标。 |
| 关键词: 子宫内膜异位性疾病 舌象 脉象 数字化技术 智能诊断 |
| DOI：10.16781/j.CN31-2187/R.20230267 |
| 投稿时间：2023-05-14修订日期：2023-09-04 |
| 基金项目:国家自然科学基金面上项目（82074475），国家自然科学基金青年科学基金（82004398），上海市卫生健康委员会海派中医流派传承创新团队建设项目（2021LPTD-002），中医妇科专科联盟资助项目[ZY (2021-2023)0302]，上海市“十三五”临床重点专科（中医妇科）项目（shslczdzk04501），张婷婷教授上海市名老中医学术经验研究工作室（SHGZS-20222）. |
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| Objective indicators of tongue and pulse manifestations in endometriosis diseases |
| ZHENG Xu1,ZHUANG Mengfei1,ZENG Weiwei2,SHEN Li3,ZHANG Tingting1*,TU Liping4,XU Jiatuo4,ZHU Xinyi5 |
(1. Department of Gynecology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China;
2. Department of Gynecology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200000, China;
3. Department of Traditional Chinese Medicine, Beicai Community Health Service Center, Pudong New Area, Shanghai 201204, China;
4. School of Basic Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China;
5. Department of Critical Care Medicine, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
* Corresponding author) |
| Abstract: |
| Objective To explore the objective indicators of tongue and pulse manifestations in patients with endometriosis diseases by collecting the data of tongue and pulse manifestations of patients with endometriosis diseases by digital tongue and pulse diagnostic instrument. Methods The endometriosis disease group included 72 patients with endometriosis diseases who were treated in Department of Gynecology (Professor ZHANG Tingting), Yueyang Hospital of Integrated Traditional Chinese and Western Medicine from Jun. 1, 2021 to Sep. 15, 2022. The normal group included 35 healthy adult women recruited by the Physical Examination Center of Shuguang Hospital, Shanghai University of Traditional Chinese Medicine. Results In terms of age, there was no significant difference between the endometriotic disease group and normal group (P＞0.05). In terms of tongue color, the values of zhiCon, zhiASM, zhiENT, zhiMEAN, zhiClrB, zhiClrI, zhiClrLa, zhiClrCb, and zhiClrLb in the endometriosis disease group were significantly different from those in the normal group (all P＜0.05), while there were no significant differences in the values of zhiClrR, zhiClrG, zhiClrS, zhiClrL, zhiClrY, or zhiClrCr between the 2 groups (all P＞0.05). In terms of tongue coating color, the values of taiClrR, taiClrB, taiClrI, taiClrS, taiClrLa, taiClrLb, taiClrCr, and taiClrCb in the endometriosis disease group were significantly different from those in the normal group (all P＜0.05), while there were no significant differences in the values of taiClrG, taiClrL, or taiClrY (all P＞0.05). In terms of texture and thickness of tongue coating, there were no significant differences in the values of perAll, perPart, taiCon, taiASM, taiENT, or taiMEAN between the 2 groups (all P＞0.05). In terms of pulse manifestation, the values of h3, h4, h5, t4, h3/h1, and h4/h1 in the endometriosis disease group were significantly different from those in the normal group (all P＜0.05), while there were no significant differences in the values of h1, t, t1, or t5 (all P＞0.05). Conclusion There are significant differences in tongue and pulse indicators between patients with endometriosis diseases and healthy individuals. It can provide objective indicators for further research on the pathogenesis changes and clinical differentiation of endometriosis diseases. |
| Key words: endometriosis diseases tongue manifestation pulse manifestation digital technology intelligent diagnosis |
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