| 摘要: |
| 幽门螺杆菌（H. pylori）感染是胃癌最重要的可控危险因素，根除H. pylori是我国胃癌防控的必经之路。以家庭为单位进行H. pylori感染筛查与治疗是切实符合我国国情的H. pylori感染管理和控制策略。该策略具有更高的H. pylori根除成功率与更低的复发率，同时具有更好的效益成本比，无论在H. pylori高感染地区还是低感染地区均适合推行。在此策略的指导下，我国的胃癌防控工作必将更加精准、高效、全面，为全球胃癌防控工作提供可推广的“中国方案”。 |
| 关键词: 幽门螺杆菌 家庭感染 根除治疗 胃肿瘤 防治策略 |
| DOI：10.16781/j.CN31-2187/R.20240812 |
| 投稿时间：2024-12-02修订日期：2024-12-25 |
| 基金项目: |
|
| Family-based strategy for prevention and control of Helicobacter pylori infection in China |
| LAI Yongkang,ZHOU Xianzhu,DU Yiqi,LI Zhaoshen* |
(Department of Gastroenterology, The First Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| Helicobacter pylori (H. pylori) infection is the most significant controllable risk factor for gastric cancer, and its eradication is a critical component of gastric cancer prevention in China. A family-based screening and treatment strategy for H. pylori aligns well with China’s public health needs. It demonstrates higher eradication success rate, lower recurrence rate, and superior cost-effectiveness, making it suitable for both high- and low-prevalence regions. Implementation of this family-based strategy can lead to greater precision, higher efficiency, and overall coverage in gastric cancer prevention in China, offering a scalable “China model” for global gastric cancer control. |
| Key words: Helicobacter pylori family infection eradication therapy gastric neoplasms prevention and control strategies |
