| 摘要: |
| 慢性阻塞性肺疾病（COPD）是一种最常见的慢性肺疾病，其主要特征是慢性不可逆性气道受阻。患者长期气流受限引起大脑供氧量减少，易引起大脑功能与结构的一系列改变。近年来很多MRI技术应用于COPD患者的研究。本文主要从静息态功能磁共振成像、基于体素的形态测量及弥散张量成像3个方面，对基于脑功能与结构成像技术在COPD中的研究进展进行综述。 |
| 关键词: 慢性阻塞性肺疾病 静息态功能磁共振成像 基于体素的形态测量 弥散张量成像 |
| DOI：10.16781/j.CN31-2187/R.20220298 |
| 投稿时间：2022-04-12修订日期：2022-11-14 |
| 基金项目:国家自然科学基金重点项目（81930049）. |
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| Application of functional and structural magnetic resonance imaging of brain in chronic obstructive pulmonary disease: research progress |
| YU Qingyang,LIU Shiyuan* |
(Department of Radiology, The Second Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200003, China
*Corresponding author) |
| Abstract: |
| Chronic obstructive pulmonary disease (COPD) is one of the most common chronic lung diseases, which is characterized by chronic irreversible airway obstruction. Chronic airflow restriction causes a decrease in oxygen supply to the brain, which inevitably leads to a series of changes in brain function and structure. In recent years, many magnetic resonance imaging (MRI) technology has been applied to explore the brain function and structure of COPD. Resting-state functional MRI, voxel-based morphometry, and diffusion tensor imaging are reviewed in this article to discuss the recent research progress of brain function and structure imaging study in COPD. |
| Key words: chronic obstructive pulmonary disease resting-state functional magnetic resonance imaging voxel-based morphometry diffusion tensor imaging |
