| 摘要: |
| 目的：探讨外用中药脱痂膏对深度烧伤创面的脱痂机制。方法：取经脱痂膏和Ag-SD霜换药的深Ⅱ度烧伤创面组织标本及渗液，用抗CD68单抗标记深度烧伤创面组织中的巨噬细胞，并计数创面渗液细菌，比较两组间的差异。结果：使用脱痂膏的创面组织含有较多的CD68＋细胞(巨噬细胞)，而创面渗液细菌数量与Ag-SD组无明显区别。结论：脱痂膏通过招引巨噬细胞至创面局部，吞噬和分解坏死组织，从而达到脱痂的目的。 |
| 关键词: 烧伤 脱痂膏 巨噬细胞 |
| DOI： |
|
| 基金项目: |
|
| The effect of Traditional Chinese Medicine Tuojiagao on burn wound |
| 葛绳德,刘世康,戴方平,韦多,王璐,白刚,陈玉林,孙家玲,俞为荣 |
| () |
| Abstract: |
| Objective: To study the mechanism of Traditional Chinese Medicine Tuojiagao in cleaning necrotic and denatured tissue in deep burn wound. Methods: Two groups of patients with deep burn wound were studied: (1) Traditional Chinese Medicine Tuojiagao group, (2) Ag-SD frost group. Tissue and exudate of the wound were collected. Macrophages were marked with anti-CD68 antibody in tissue slides. The bacteria of wound exudate were counted. Results: The sections from wounds after using Tuojiagao have more CD68+ cells (macrophages) than Ag-SD group, and no difference of bacteria count was found between the 2 groups. Conclusion: Tuojiagao could clean necrotic tissue through recruiting macrophages to scavenge and break down it. |
| Key words: burns Tuojiagao macrophages |
