| 摘要: |
| 目的：制备适合高原地区使用的防晒、防裂护肤霜。方法：选用疏水性强、润滑涂展性好、能抗高寒气流的聚甲基硅氧烷为主要基质，壬基酚聚氧乙烯醚（OP）为主要乳化剂，附加其他多种防晒护肤成分制得O/W型高原护肤霜。抗紫外线实验采用氯丙嗪在光照下发生光毒反应模型，从光毒反应的减轻程度反映霜剂抗紫外线作用的强弱。结果：动物实验表明，高原护肤霜具有显著的抗紫外线效果，优于擦脸油产品，且对皮肤、角膜等均无刺激性和过敏反应发生。结论：高原护肤霜具有可靠的防晒作用，建议作为一种特殊防护用品装备部队使用。 |
| 关键词: 高原护肤霜 抗紫外线 |
| DOI： |
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| 基金项目: |
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| Preparation of Gaoyuan skin care cream and its antiultraviolet effect |
| 柳正良,张川,孙其荣,蒋雪涛,钟延强 |
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| Abstract: |
| Objective： To prepare Gaoyuan skin care cream （O/W） for plateau environment. Methods: Gaoyuan skin care cream （O/W） was specially prepared with OP，silicon，Salol，VitE，TiO2, etc. Test of antiultraviolet were performed using photoxic reaction model of chloromazine. Results: Stabilization test demonstrated that the cream had an excellent physical and chemical stability. The effect of antiultraviolet of Gaoyuan skin care cream was higher than that of control group (P<0.01). Conclusion: The effect of antiultraviolet is excellent and it is a safe and effective cream. |
| Key words: Gaoyuan skin cream antiultraviolet |
