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肝干细胞在肝再生中的作用
李维卿,余宏宇*
0
(第二军医大学长征医院病理科,上海 200003)
摘要:
肝干细胞移植可能是治疗终末期肝病的重要途径之一,因而肝干细胞成为研究的热点。不同来源的肝干细胞具有强大的临床治疗潜能,但是在临床应用普遍推行之前,有许多研究工作需要进一步开展。本综述就肝干细胞的一些基本特性及其在肝脏损伤后的肝再生作用展开讨论。
关键词:  肝干细胞  肝损伤  肝再生
DOI:10.3724/SP.J.1008.2008.00694
投稿时间:2007-12-05修订日期:2007-12-27
基金项目:国家自然科学基金(30570836).
Role of hepatic stem cells in hepatic regeneration
LI Wei-qing, YU Hong-yu*
(Department of Pathology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China)
Abstract:
Hepatic stem cells transplantation might be an important treatment strategy for patients with end stage liver diseases and related research has become a focus of recent studies. Hepatic stem cells of different sources have great therapeutic potential in clinical practice, but much research still need to be done before it can be used as a routine method in clinical practice. This review discusses the characteristics of hepatic stem cells and its role in liver regeneration after liver damage.
Key words:  hepatic stem cells  liver injuries  liver regeneration