| 摘要: |
| 目的研究爱康肤银离子敷料在小儿浅Ⅱ度烧伤创面治疗中的作用。方法采用同体对照法,在40例烧伤患儿身上分别选取2处面积相当的浅Ⅱ度创面,随机分为2组,对照组用磺胺嘧啶银霜换药治疗,治疗组则用爱康肤银离子敷料。分别统计两组创面的愈合时间、愈合率、病程早期渗出量、平均换药次数、平均更换最内层药用纱布次数,并取创面分泌物进行细菌培养,同时定期监测受试者在用药期间有无实验室检测指标异常及不良反应。结果与对照组相比,治疗组的创面愈合时间缩短(P＜0.05),用药后第3、7、14天创面愈合率均增高(P＜0.05,P＜0.01),创面渗出量、平均换药次数及平均更换最内层药用纱布次数均降低(P＜0.01)。两组创面细菌培养阳性率的差异无统计学意义。治疗期间所有受试患儿出现的实验室检测指标差异与药物不存在明显相关,绝大多数患儿无不适主诉。结论应用爱康肤银离子敷料治疗小儿浅Ⅱ度烧伤,能有效缩短创面愈合时间,提高创面愈合率,明显减少创面渗出及换药频率,其抑菌效果与浅Ⅱ度烧伤的经典创面外用药磺胺嘧啶银霜相比无明显差异,且在治疗期间绝大多数患儿未出现不良反应,值得在临床上进一步推广应用。 |
| 关键词: 烧伤 爱康肤银 敷料 伤口愈合 |
| DOI：10.3724/SP.J.1008.2011.01321 |
| 投稿时间：2011-10-13修订日期：2011-11-15 |
| 基金项目: |
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| Clinical application of Aquacel-Ag dressing in treatment of pediatric superficial Ⅱ burn wounds |
| ZHOU Pan-yu, XIA Zhao-fan*, BEN Dao-feng, MA Bing, FANG He, FENG Ping |
(Department of Burn Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
*Corresponding author.) |
| Abstract: |
| ObjectiveTo evaluate the clinical effects of Aquacel-Ag dressing in treatment of pediatric superficial Ⅱ burn wound. MethodsForty patients fulfilling the inclusion criteria were included in the present study. Two burn wound areas of similar size were selected from each patient and were randomly divided into two groups. The burn areas in the control group were covered with SD-Ag and those in the treatment group were managed with Aquacel-Ag dressing. The healing time, recovering rate, seepage amount, the frequency of dressing changes and frequency of changing the inner most layer gauze were compared between the two groups. Meanwhile, the laboratory abnormalities and adverse effect were closely monitered during the treatment. ResultsCompared with the SD-Ag group, the Aquacel-Ag dressing group exhibited a significantly shorter healing time (P＜0.05); it also had higher recovering rates (P＜0.05, P＜0.01) on the 3rd, 7th and 14th day after treatment; moreover, Aquacel-Ag dressing also resulted in significantly lower seepage amount and reduced dressing changes (P＜0.01). However, the outcomes of bacterial culture were not significantly different between the two groups (P＞0.05). We also found there was no direct relationship between the laboratory abnormalities and the therapeutic measures during the study, and most patients had no uncomfortable chief complaint. ConclusionAquacel-Ag dressing can shorten the healing time, improve healing rate, reduce seepage amount, and decrease frequency of dressing change for superficial Ⅱ burn wound in pediatric patients. And it has an antimicrobial property similar to SD-Ag for superficial Ⅱ burn wound and shows no noticeable adverse effect. |
| Key words: burns Aquacel-Ag dressings wound healing |
