| 摘要: |
| 膀胱癌是一种严重危害人类健康的恶性肿瘤，但其诊治进展较为缓慢。随着分子生物学的快速发展和生物检测技术的不断涌现，通过基因分析技术对膀胱癌进行分子分型有望成为提高膀胱癌诊治水平的重要手段。本文就近年来膀胱癌分子分型的研究进展以及膀胱癌分子分型对预测药物反应性和判断预后的临床价值作一综述。 |
| 关键词: 膀胱癌 分子分型 基因分析 预后 耐药性 |
| DOI：10.16781/j.0258-879x.2018.01.0081 |
| 投稿时间：2017-09-22修订日期：2017-11-06 |
| 基金项目: |
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| Molecular typing of bladder cancer: an update |
| WANG Kai-jian,DAI Li-he,XU Chuan-liang* |
(Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| Bladder cancer is one of the malignant tumors that seriously endanger human health, but its diagnosis and treatment progress are relatively slow. With the rapid development of molecular biology and the continuous emergence of biological detection technology, the molecular typing of bladder cancer through gene analysis is expected to become an important means to improve the diagnosis and treatment of bladder cancer. In this paper, we summarized the recent advances in the molecular typing of bladder cancer and its clinical significance in predicting drug responsiveness and judging prognosis. |
| Key words: bladder carcinoma molecular typing gene analysis prognosis drug resistance |
