| 摘要: |
| 我国是消化道肿瘤高发国家，也是胃癌发病率和幽门螺杆菌（H.pylori）感染率双高国家。H.pylori是胃癌的明确致癌物，同时也是胃癌最重要的可控危险因素。根除H.pylori的时机越早越好，对于已发生肠上皮化生的患者通过根除H.pylori也可获益。H.pylori感染的管理策略已经从“检测和治疗”“筛查和治疗”向“以家庭为单位防控”转变。筛查并根除H.pylori是降低我国胃癌发生率的可行途径。 |
| 关键词: 胃肿瘤 筛查 幽门螺杆菌 根除治疗 预防 |
| DOI：10.16781/j.CN31-2187/R.20220597 |
| 投稿时间：2022-07-18修订日期：2022-08-30 |
| 基金项目:上海市卫生健康委员会先进适宜技术推广项目（2019SY001）. |
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| Prevention and treatment of Helicobacter pylori infection is a feasible way to prevent gastric cancer |
| ZHOU Xian-zhu,DU Yi-qi* |
(Department of Gastroenterology, The First Affiliated Hospital of Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author) |
| Abstract: |
| China is a country with a high incidence of gastrointestinal cancer, as well as a country with a high incidence of gastric cancer and a high infection rate of Helicobacter pylori (H.pylori). H.pylori is a definite carcinogen of gastric cancer, hence is the most important controllable risk factor of gastric cancer. The earlier to eradicate H.pylori, the better outcomes could be obtained. For patients with intestinal metaplasia, can also benefit from eradicating H.pylori. The management strategy for H.pylori infection has been changed from “test and treat”, “screening and treat” to “family-based prevention and control”. Screening and eradicating H.pylori is a feasible way to reduce the incidence of gastric cancer in China. |
| Key words: stomach neoplasms screening Helicobacter pylori eradication prevention |
