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| 聚丙烯/多孔聚四氟乙烯/聚丙烯复合驻极体的储电性能 |
| 宋茂海1,孔玉秀2,程亮1,王冬2,肖永恒2,崔黎丽2,江键1* |
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| (1.第二军医大学基础部数理学教研室,上海 200433;2.第二军医大学药学院无机化学教研室,上海 200433) |
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| 摘要: |
| 目的:考察聚丙烯(PP)/多孔聚四氟乙烯(PTFE)/PP复合驻极体的储电性能。方法:利用热融法将多孔PTFE、聚乙烯(PE)和PP制备成PP/多孔PTFE/PP复合膜驻极体,利用等效表面电位衰减和开路热刺激放电(TSD)电流谱方法研究PP/多孔PTFE/PP驻极体的电荷储存稳定性及其输运规律。结果:(1)热融过程改变了空间电荷在PP/多孔PTFE/PP驻极体内部各能阱中的分布比例,使PP/多孔PTFE/PP复合驻极体的电荷储存稳定性优于常温注极的PP驻极体；(2)PP/多孔PTFE/PP驻极体在高湿环境下仍具有良好的电荷储存稳定性。结论:PP/多孔PTFE/PP复合膜驻极体具有良好的电荷储电稳定性,可作为激励源用于促药物透皮吸收制剂的研制。 |
| 关键词: 静电场 驻极体 聚丙烯 多孔聚四氟乙烯 聚丙烯 皮肤投药 |
| DOI：10.3724/SP.J.1008.2009.0481 |
| 投稿时间：2008-10-13修订日期：2009-03-23 |
| 基金项目:国家自然科学基金(50577066)；军队“十一五”国际合作项目(06H022). |
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| Charge storage stability of electret film made of polypropylene/porous polytetrafluoroethylene/polypropylene composite |
| SONG Mao-hai1,KONG Yu-xiu2,CHENG Liang1,WANG Dong2,XIAO Yong-heng2,CUI Li-li2,JIANG Jian1* |
| (1.Department of Physics and Mathematics,College of Basic Medical Sciences,Second Military Medical University,Shanghai 200433,China;2.Department of Inorganic Chemistry,School of Pharmacy,Second Military Medical University,Shanghai 200433) |
| Abstract: |
| Objective:To study charge storage stability of electret film made of polypropylene(PP)/porous polytetrafluoroethylene(PTFE)/polypropylene composite.Methods: The PP/porous PTFE/PP composite electret film was prepared with porous PTFE,polyethylene(PE) and PP by heat melting technique.The charge storage stability of the electret film and transportation were evaluated by using the methods of isothermal surface potential attenuation and open-circuit thermally stimulated discharge (TSD) current spectra.Results:(1) The charge storage stability of PP/porous PTFE/PP composite electret was superior to that of PP electret made under ordinary temperature,because the space charge of PP/porous PTFE/PP electret was transferred from deep trap to flat trap during the heat melting process.(2) Satisfactory charge storage stability was observed in PP/porous PTFE/PP electret when under the condition of high humidity.Conclusion:PP/porous PTFE/PP electret film has satisfactory charge storage stability and can be used as a novel enhancer in transdermal delivery of drugs. |
| Key words: electrostatics field electret polypropylene porous polytetrafluoroethylene polyethylene cutaneous administration |
