| 摘要: |
| 如何维持长期良好的移植物功能是目前肾移植领域面临的最为突出的问题。鉴于现有诊断手段的种种缺陷,其相关生物标志物的研究已在不同的生物学层面广泛开展,且进展迅速。本文拟对近年来与肾移植长期存活相关的生物标志物的研究现状作简要综述。 |
| 关键词: 肾移植 生物学标志物 慢性移植物失功 慢性移植肾肾病 长期存活 |
| DOI：10.3724/SP.J.1008.2012.0212 |
| 投稿时间：2011-06-02修订日期：2011-12-09 |
| 基金项目: |
|
| Biomarkers for long-term survival of renal graft: recent progress |
| ZHANG Xin,WANG Li-ming* |
(Department of Organ Transplantation, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
*Corresponding author.) |
| Abstract: |
| How to maintain a good long-term graft function is currently the most prominent problem in renal transplantation. Due to inefficiency of the existing diagnostic tools, extensive studies have been made to search for novel biomarkers and have made rapid progression. Here we aimed to make a brief review of important biomarkers that have been shown relevant to the long-term outcome of renal graft. |
| Key words: renal transplantation biomarker chronic allograft dysfunction chronic allograft nephropathy long-term suvival |
