| 摘要: |
| 目的 探讨Camdessanché诊断标准在中国人感觉神经元病(SNN)中的临床应用价值。方法 收集2008年12月至2014年11月我院临床诊断的6例SNN及同期临床症状类似的6例非SNN(non-SNN)患者的临床、生化、电生理资料, 应用Camdessanché诊断标准进行诊断评估, 并与临床经验性诊断结果进行对照。 结果 采用 Camdessanché 诊断标准, 4例临床诊断SNN的患者诊断为很可能的SNN, 2例SNN和1例non-SNN患者诊断为可能的SNN。结论 Camdessanché诊断标准中“很可能”的分级诊断对国人SNN患者诊断价值较大, 相关结论仍有待进一步大样本研究证实。 |
| 关键词: 感觉神经元病 Camdessanché诊断标准 电生理学 诊断 |
| DOI：10.3724/SP.J.1008.2015.00564 |
| 投稿时间：2014-12-03修订日期：2015-04-06 |
| 基金项目:上海市科委实验动物专项基金(13140903400),上海市申康医院发展中心慢性病综合防治项目(SHDC12012314),第二军医大学长海医院“1255”学科建设计划(CH125530900). |
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| Application of Camdessanché's diagnostic criteria for sensory neuronopathies in Chinese |
| GAO Rui1,HAN Lu1,ZHOU Xia-jun1,GUAN Yang-tai1,2* |
(1. Department of Neurology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China;
2. Department of Neurology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200001, China
*Corresponding author) |
| Abstract: |
| Objective To evaluate the clinical value of Camdessanché's criteria for diagnosis of patients with sensory neuronopathies (SNN). Methods We retrospectively analyzed the clinical, biochemical and electrophysiological data of 6 patients diagnosed as having SNN and 6 patients with non-SNN disease (but with similar symptoms), who were treated in Changhai Hospital from Dec. 2008 to Nov. 2014. Then the Camdessanché's criteria were used for diagnosis of SNN in the 12 patients, and the results were compared with those of empirical diagnosis. Results Four of the 6 SNN patients were classified as probable to have SNN by the Camdessanché's criteria; and two of the 6 SNN patients and one of the 6 non-SNN patients were classified as possible to have SNN. Conclusion The “probable” diagnosis of SNN in the Camdessanché's criteria has a greater value for diagnosis of SNN in Chinese, which still needs to be further confirmed by large sample study. |
| Key words: sensory neuronopathies Camdessanché's diagnostic criteria electrophysiology diagnosis |
