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低强度脉冲超声在肌肉骨骼疾病中的研究进展
张子程1,胡建辉2,杨依林1,周潇逸1,魏显招1,李明1*
0
(1. 海军军医大学(第二军医大学)长海医院脊柱外科, 上海 200433;
2. 海军军医大学(第二军医大学)长海医院医务处, 上海 200433
*通信作者)
摘要:
低强度脉冲超声(LIPUS)是一种非侵入性的治疗方式,其被广泛应用于肌肉骨骼系统疾病的治疗。早期LIPUS主要应用于新鲜骨折、骨不连的治疗,近年来发现LIPUS对软骨组织损伤、椎间盘退变等软组织疾病也有治疗作用。此外,LIPUS也应用于骨科手术中,如牵拉成骨术和脊柱融合术。随着对LIPUS作用机制研究的逐渐深入,其临床应用前景将更广泛。本文对LIPUS在肌肉骨骼系统疾病中的研究及应用进展作一综述。
关键词:  低强度脉冲超声  骨折  骨不连  软骨组织损伤  椎间盘退变  肌肉骨骼疾病
DOI:10.16781/j.0258-879x.2020.02.0194
投稿时间:2019-10-13修订日期:2020-01-07
基金项目:国家自然科学基金(81900809),上海市卫生系统优秀人才培养计划(2018YQ26),长海医院院级科研项目(2018QNA013).
Research progress of low-intensity pulsed ultrasound in the treatment of musculoskeletal diseases
ZHANG Zi-cheng1,HU Jian-hui2,YANG Yi-lin1,ZHOU Xiao-yi1,WEI Xian-zhao1,LI Ming1*
(1. Department of Spinal Surgery, Changhai Hospital, Naval Medical University(Second Military Medical University), Shanghai 200433, China;
2. Division of Medical Affairs, Changhai Hospital, Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
Low-intensity pulsed ultrasound (LIPUS) is a non-invasive treatment widely used in the treatment of musculoskeletal diseases. In the early stage, LIPUS was mainly used in fresh fracture and nonunion. In recent research, the therapeutic effect of LIPUS on cartilage tissue injury, intervertebral disc degeneration and other soft tissue diseases has also been noted. Moreover, LIPUS is also used in the orthopaedic surgery such as distraction osteogenesis and spinal fusion. With research on the mechanism of LIPUS progressing, its clinical application will become more extensive. This article reviews the research and application of LIPUS in musculoskeletal diseases.
Key words:  low-intensity pulsed ultrasound  fracture  nonunion  cartilage injury  disc degeneration  musculoskeletal diseases