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胰腺癌腹腔转移诊断方式的研究进展
孟尧,陈高齐,马靖雯,胡昊,何天霖*
0
(海军军医大学(第二军医大学)第一附属医院肝胆胰脾外科, 上海 200433
*通信作者)
摘要:
转移发生较早是胰腺癌预后差的重要因素之一。及早发现腹腔转移能够促使患者尽早接受新辅助治疗和转化治疗,避免了非必要的手术创伤。本文综述了影像学方法、实验室方法及联合多方式综合评估等手段对胰腺癌腹腔转移的诊断效能,简述了CT、MRI、超声、肿瘤标志物及miRNA检测等方式在胰腺癌腹腔转移中的应用,并总结了部分采用多类指标综合评判从而提高转移风险预测能力的相关研究成果,以期为临床诊断方式的选择和应用提供借鉴。
关键词:  胰腺肿瘤  腹腔转移  诊断效能  预测能力
DOI:10.16781/j.CN31-2187/R.20220121
投稿时间:2022-02-08修订日期:2022-09-02
基金项目:上海市医苑新星杰出青年医学人才计划(2019020).
Diagnosis of abdominal metastasis of pancreatic cancer: research progress
MENG Yao,CHEN Gao-qi,MA Jing-wen,HU Hao,HE Tian-lin*
(Department of Hepatobiliary, Pancreatic and Splenic Surgery, The First Affiliated Hospital of Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
Early metastasis is one of the important factors for poor prognosis of pancreatic cancer. Early detection of abdominal metastasis can urge patients to undergo neoadjuvant therapy and conversion therapy as soon as possible and avoid unnecessary surgical trauma. This paper reviews the diagnostic efficacy of imaging methods, laboratory methods and combined multi-mode comprehensive evaluation in patients with abdominal metastasis of pancreatic cancer, briefly describing the application of computed tomography, magnetic resonance imaging, ultrasound, tumor markers, microRNA and other methods, and summarizing the use of multi-index comprehensive evaluation to improve the ability of metastasis risk prediction, so as to provide reference for the selection and application of clinical diagnostic methods.
Key words:  pancreatic neoplasms  abdominal metastasis  diagnostic efficacy  predictive ability