| 摘要: |
| 睡眠对内分泌功能及能量代谢起着重要的调节作用。睡眠剥夺后,激素水平会发生显著变化。睡眠剥夺能够影响3种下丘脑-垂体轴激素(生长激素、促甲状腺激素和皮质醇)在夜间的分泌。同时,睡眠缺失还会破坏瘦素同ghrelin的相对平衡,对能量代谢产生不利影响。 |
| 关键词: 睡眠剥夺；内分泌；代谢 失眠 |
| DOI：10.3724/SP.J.1008.2008.00703 |
| 投稿时间：2007-07-14修订日期：2008-02-15 |
| 基金项目:上海市科技发展基金(024119029)；第二军医大学长征医院“三重三优”学科人才建设计划基金（2005312）. |
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| Influence of sleep deprivation on endocrine function and energy metabolism |
| LI Yan-peng,ZHAO Zhong-xin* |
| (Department of Neurology,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China) |
| Abstract: |
| Sleep plays an important role in the modulation of endocrine function and energy metabolism;hormone levels are markedly different during a sleepless night compared with a night of normal sleep.Sleep deprivation may change the levels of cortisol,growth hormone (GH) and thyrotropin (TSH) at night.In addition,sleep curtailment disturbs the balance of anorexigenic (leptin) and orexigenic (ghrelin) factors,and does harmful to glucose tolerance. |
| Key words: sleep deprivation endocrine metabolism insomnia |
