| 摘要: |
| 随着各类恶性肿瘤发病率的逐年增长及患者带瘤存活时间的延长，肿瘤本身及抗肿瘤治疗所引起的癌因性疲乏（CRF）对患者的社交、情绪、睡眠和生存期等造成越来越显著的负面影响。目前CRF发生机制尚不明确且西医治疗效果不佳。本文回顾中医药治疗CRF的相关研究进展，发现中医药在固本培元的治疗原则下，采用中成药、穴位刺激、导引运动等措施可有效缓解CRF。同时中医药在治疗CRF中注重脾肾同补以培固元气及相关机制的研究，从而减轻CRF患者的痛苦，提高患者生存质量，凸显癌症诊疗过程中的人文关怀。 |
| 关键词: 癌因性疲乏 中医药疗法 恶性肿瘤 虚劳 固本培元 |
| DOI：10.16781/j.CN31-2187/R.20220811 |
| 投稿时间：2022-10-19修订日期：2022-12-24 |
| 基金项目:国家自然科学基金（82273074），上海市自然科学基金（22ZR1477900），上海市临床重点专科项目（shslczdzk02402）. |
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| Role and mechanism of traditional Chinese medicine treatment in cancer-related fatigue based on consolidating basis and cultivating primordial qi theory: research progress |
| JIAO Weiyi1,2,WANG Mingda2,YANG Tian2,SHEN Feng1,2* |
(1. Guangdong Pharmaceutical University, Guangzhou 510006, Guangdong, China;
2. Department of Hepatobiliary Surgery, The Third Affiliated Hospital of Naval Medical University (Second Military Medical University), Shanghai 200438, China
*Corresponding author) |
| Abstract: |
| With the increasing incidence of various malignancies and the patients' prolonged time of surviving with tumors, cancer-related fatigue (CRF) caused by tumor or anti-tumor therapies has an increasingly significant negative impact on sociality, emotion, sleep, and survival of patients. The underlying mechanism of CRF is unclear and the efficacy of Western medicine treating CRF is unsatisfactory. This paper reviews the relevant research progress of traditional Chinese medicine (TCM) in the treatment of CRF. With the guidance of TCM principle "consolidating basis and cultivating primordial qi", treatments including Chinese patent medicine, acupoint stimulation, and guided exercise can effectively alleviate CRF. Meanwhile, TCM treatment for CRF emphasizes studying the relevant mechanism and tonifying the spleen and kidney to strengthen qi, so as to reduce the pain of CRF patients, improve the quality of life of patients, and enhance the humanistic care in the process of tumor diagnosis and treatment. |
| Key words: cancer-related fatigue traditional Chinese medicine therapy malignant tumor consumptive disease consolidating basis and cultivating primordial qi |
